BDBM50193253 CHEMBL3961676
SMILES: Cl.CN(C)CCOc1ccc(cc1)C(=C(\CCCF)c1ccccc1)\c1ccc(O)cc1
InChI Key: InChIKey=KXTIGEUSLGAAHZ-JTHROIFXSA-N
Data: 5 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Estrogen-related receptor gamma (Homo sapiens (Human)) | BDBM50193253 (CHEMBL3961676) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Daegu-Gyeongbuk Medical Innovation Foundation Curated by ChEMBL | Assay Description Inverse agonist activity at ERRgamma (unknown origin) expressed in human AD293 cells after 24 hrs by beta-galactosidase/luciferase reporter gene assa... | Eur J Med Chem 120: 338-52 (2016) Article DOI: 10.1016/j.ejmech.2016.04.076 BindingDB Entry DOI: 10.7270/Q2TH8PN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen-related receptor gamma (Homo sapiens (Human)) | BDBM50193253 (CHEMBL3961676) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Daegu-Gyeongbuk Medical Innovation Foundation Curated by ChEMBL | Assay Description Inhibition of fluorescien-conjugated coactivator PGC1a binding to GST-tagged human ERRgamma LBD after 1 hr by TR-FRET assay | Eur J Med Chem 120: 338-52 (2016) Article DOI: 10.1016/j.ejmech.2016.04.076 BindingDB Entry DOI: 10.7270/Q2TH8PN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Steroid hormone receptor ERR2 (Homo sapiens (Human)) | BDBM50193253 (CHEMBL3961676) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 722 | n/a | n/a | n/a | n/a | n/a | n/a |
Daegu-Gyeongbuk Medical Innovation Foundation Curated by ChEMBL | Assay Description Inhibition of fluorescien-conjugated coactivator PGC1a binding to ERRbeta (unknown origin) after 1 hr by TR-FRET assay | Eur J Med Chem 120: 338-52 (2016) Article DOI: 10.1016/j.ejmech.2016.04.076 BindingDB Entry DOI: 10.7270/Q2TH8PN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen-related receptor alpha (Homo sapiens (Human)) | BDBM50193253 (CHEMBL3961676) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Daegu-Gyeongbuk Medical Innovation Foundation Curated by ChEMBL | Assay Description Inhibition of fluorescien-conjugated coactivator PGC1a binding to ERRalpha (unknown origin) after 1 hr by TR-FRET assay | Eur J Med Chem 120: 338-52 (2016) Article DOI: 10.1016/j.ejmech.2016.04.076 BindingDB Entry DOI: 10.7270/Q2TH8PN2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM50193253 (CHEMBL3961676) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Daegu-Gyeongbuk Medical Innovation Foundation Curated by ChEMBL | Assay Description Inhibition of fluorescien-conjugated coactivator PGC1a binding to ERalpha (unknown origin) after 1 hr by TR-FRET assay | Eur J Med Chem 120: 338-52 (2016) Article DOI: 10.1016/j.ejmech.2016.04.076 BindingDB Entry DOI: 10.7270/Q2TH8PN2 | |||||||||||
More data for this Ligand-Target Pair |