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BDBM50193270 CHEMBL3904163

SMILES: Cl.CN(C)CCOc1ccc(cc1)C(=C(\CCCO)c1ccccc1)\c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=SGDDJXUXCKQQMO-JTHROIFXSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193270   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Estrogen-related receptor gamma


(Homo sapiens (Human))		BDBM50193270
PNG
(CHEMBL3904163)
Show SMILES Cl.CN(C)CCOc1ccc(cc1)C(=C(\CCCO)c1ccccc1)\c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C28H30F3NO2.ClH/c1-32(2)18-20-34-25-16-12-23(13-17-25)27(22-10-14-24(15-11-22)28(29,30)31)26(9-6-19-33)21-7-4-3-5-8-21;/h3-5,7-8,10-17,33H,6,9,18-20H2,1-2H3;1H/b27-26-;
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PC cid
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Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL


Assay Description
Inhibition of fluorescien-conjugated coactivator PGC1a binding to GST-tagged human ERRgamma LBD after 1 hr by TR-FRET assay

Eur J Med Chem 120: 338-52 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.076
BindingDB Entry DOI: 10.7270/Q2TH8PN2
More data for this
Ligand-Target Pair