new BindingDB logo
myBDB logout

BDBM50193472 CHEMBL378656::N-(3-(2-aminoethyl)-4-methoxyphenyl)benzenesulfonamide

SMILES: COc1ccc(NS(=O)(=O)c2ccccc2)cc1CCN

InChI Key: InChIKey=AZDBAJSZMDQOTI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193472   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50193472
PNG
(CHEMBL378656 | N-(3-(2-aminoethyl)-4-methoxyphenyl...)
Show SMILES COc1ccc(NS(=O)(=O)c2ccccc2)cc1CCN
Show InChI InChI=1S/C15H18N2O3S/c1-20-15-8-7-13(11-12(15)9-10-16)17-21(18,19)14-5-3-2-4-6-14/h2-8,11,17H,9-10,16H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
17n/an/an/an/an/an/an/an/a



Virginia Commonwealth University

Curated by ChEMBL


Assay Description
Binding affinity to human 5HT6 receptor in HEK293 cells by radioligand binding assay


J Med Chem 49: 5217-25 (2006)


Article DOI: 10.1021/jm060469q
BindingDB Entry DOI: 10.7270/Q2416WQN
More data for this
Ligand-Target Pair