BDBM50193527 (Z)-5-[1-(2,3-dihydro-2,7-dimethyl-3-oxobenzo[d]isoxazol-5-yl)-4-(2-oxooxazolidin-3-yl)but-1-enyl]-2-methoxy-3-methylbenzoic acid methyl ester::CHEMBL215346

SMILES: COC(=O)c1cc(cc(C)c1OC)C(=C/CCN1CCOC1=O)\c1cc(C)c2on(C)c(=O)c2c1

InChI Key: InChIKey=XNBBXEBKNPSAJS-GXHLCREISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193527   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50193527 ((Z)-5-[1-(2,3-dihydro-2,7-dimethyl-3-oxobenzo[d]is...) Show SMILES COC(=O)c1cc(cc(C)c1OC)C(=C/CCN1CCOC1=O)\c1cc(C)c2on(C)c(=O)c2c1 Show InChI InChI=1S/C26H28N2O7/c1-15-11-18(14-21(22(15)32-4)25(30)33-5)19(7-6-8-28-9-10-34-26(28)31)17-12-16(2)23-20(13-17)24(29)27(3)35-23/h7,11-14H,6,8-10H2,1-5H3/b19-7-	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of recombinant HIV1 reverse transcriptase measured as inhibition of incorporation of [32P]GTP in rCDG primer				J Med Chem 49: 5316-23 (2006) Article DOI: 10.1021/jm060449o BindingDB Entry DOI: 10.7270/Q2QV3M5K
					More data for this Ligand-Target Pair