BDBM50193615 (E)-N-(4-amino-2-propylquinolin-6-yl)-3-(4-chlorophenyl)acrylamide::CHEMBL214985

SMILES: CCCc1cc(N)c2cc(NC(=O)\C=C\c3ccc(Cl)cc3)ccc2n1

InChI Key: InChIKey=WSVARIJKECKDOY-IZZDOVSWSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193615   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50193615 ((E)-N-(4-amino-2-propylquinolin-6-yl)-3-(4-chlorop...) Show SMILES CCCc1cc(N)c2cc(NC(=O)\C=C\c3ccc(Cl)cc3)ccc2n1 Show InChI InChI=1S/C21H20ClN3O/c1-2-3-16-13-19(23)18-12-17(9-10-20(18)24-16)25-21(26)11-6-14-4-7-15(22)8-5-14/h4-13H,2-3H2,1H3,(H2,23,24)(H,25,26)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	96	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Stimulation of IP3-coupled mobilization of calcium in HEK293 cells expressing MCH-R1				Bioorg Med Chem Lett 16: 5275-9 (2006) Article DOI: 10.1016/j.bmcl.2006.08.008 BindingDB Entry DOI: 10.7270/Q26T0M8S
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50193615 ((E)-N-(4-amino-2-propylquinolin-6-yl)-3-(4-chlorop...) Show SMILES CCCc1cc(N)c2cc(NC(=O)\C=C\c3ccc(Cl)cc3)ccc2n1 Show InChI InChI=1S/C21H20ClN3O/c1-2-3-16-13-19(23)18-12-17(9-10-20(18)24-16)25-21(26)11-6-14-4-7-15(22)8-5-14/h4-13H,2-3H2,1H3,(H2,23,24)(H,25,26)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of 125I-[Phe13,Tyr19]-MCH from human MCH-R1				Bioorg Med Chem Lett 16: 5275-9 (2006) Article DOI: 10.1016/j.bmcl.2006.08.008 BindingDB Entry DOI: 10.7270/Q26T0M8S
					More data for this Ligand-Target Pair