BDBM50193674 CHEMBL214125::N-(2-(2-methylpyrrolidin-1-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide

SMILES: CC1CCCN1c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1

InChI Key: InChIKey=KHHJLWFCLVTIRA-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50193674 (CHEMBL214125 | N-(2-(2-methylpyrrolidin-1-yl)quino...) Show SMILES CC1CCCN1c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C24H24F3N3O/c1-16-3-2-14-30(16)22-12-7-18-15-20(10-11-21(18)29-22)28-23(31)13-6-17-4-8-19(9-5-17)24(25,26)27/h4-5,7-12,15-16H,2-3,6,13-14H2,1H3,(H,28,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of 125I-[Phe13,Tyr19]-MCH from human MCH-R1				Bioorg Med Chem Lett 16: 5270-4 (2006) Article DOI: 10.1016/j.bmcl.2006.08.006 BindingDB Entry DOI: 10.7270/Q2ZC82HP
					More data for this Ligand-Target Pair
GPR24 (RAT)	BDBM50193674 (CHEMBL214125 | N-(2-(2-methylpyrrolidin-1-yl)quino...) Show SMILES CC1CCCN1c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C24H24F3N3O/c1-16-3-2-14-30(16)22-12-7-18-15-20(10-11-21(18)29-22)28-23(31)13-6-17-4-8-19(9-5-17)24(25,26)27/h4-5,7-12,15-16H,2-3,6,13-14H2,1H3,(H,28,31)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Stimulation of IP3-coupled mobilization of calcium in HEK293 cells expressing rat MCH-R1				Bioorg Med Chem Lett 16: 5270-4 (2006) Article DOI: 10.1016/j.bmcl.2006.08.006 BindingDB Entry DOI: 10.7270/Q2ZC82HP
					More data for this Ligand-Target Pair