BDBM50193675 CHEMBL385661::N-(2-(3-(3-methylureido)pyrrolidin-1-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide

SMILES: CNC(=O)NC1CCN(C1)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1

InChI Key: InChIKey=ICPOECOBUQHLDO-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GPR24 (RAT)	BDBM50193675 (CHEMBL385661 | N-(2-(3-(3-methylureido)pyrrolidin-...) Show SMILES CNC(=O)NC1CCN(C1)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C25H26F3N5O2/c1-29-24(35)31-20-12-13-33(15-20)22-10-5-17-14-19(8-9-21(17)32-22)30-23(34)11-4-16-2-6-18(7-3-16)25(26,27)28/h2-3,5-10,14,20H,4,11-13,15H2,1H3,(H,30,34)(H2,29,31,35)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Stimulation of IP3-coupled mobilization of calcium in HEK293 cells expressing rat MCH-R1				Bioorg Med Chem Lett 16: 5270-4 (2006) Article DOI: 10.1016/j.bmcl.2006.08.006 BindingDB Entry DOI: 10.7270/Q2ZC82HP
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50193675 (CHEMBL385661 | N-(2-(3-(3-methylureido)pyrrolidin-...) Show SMILES CNC(=O)NC1CCN(C1)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C25H26F3N5O2/c1-29-24(35)31-20-12-13-33(15-20)22-10-5-17-14-19(8-9-21(17)32-22)30-23(34)11-4-16-2-6-18(7-3-16)25(26,27)28/h2-3,5-10,14,20H,4,11-13,15H2,1H3,(H,30,34)(H2,29,31,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of 125I-[Phe13,Tyr19]-MCH from human MCH-R1				Bioorg Med Chem Lett 16: 5270-4 (2006) Article DOI: 10.1016/j.bmcl.2006.08.006 BindingDB Entry DOI: 10.7270/Q2ZC82HP
					More data for this Ligand-Target Pair