BDBM50193681 CHEMBL215648::N-(2-(isopropyl(methyl)amino)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide

SMILES: CC(C)N(C)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1

InChI Key: InChIKey=MPLZJJHETRKHRI-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193681   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50193681 (CHEMBL215648 | N-(2-(isopropyl(methyl)amino)quinol...) Show SMILES CC(C)N(C)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C23H24F3N3O/c1-15(2)29(3)21-12-7-17-14-19(10-11-20(17)28-21)27-22(30)13-6-16-4-8-18(9-5-16)23(24,25)26/h4-5,7-12,14-15H,6,13H2,1-3H3,(H,27,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of 125I-[Phe13,Tyr19]-MCH from human MCH-R1				Bioorg Med Chem Lett 16: 5270-4 (2006) Article DOI: 10.1016/j.bmcl.2006.08.006 BindingDB Entry DOI: 10.7270/Q2ZC82HP
					More data for this Ligand-Target Pair
GPR24 (RAT)	BDBM50193681 (CHEMBL215648 | N-(2-(isopropyl(methyl)amino)quinol...) Show SMILES CC(C)N(C)c1ccc2cc(NC(=O)CCc3ccc(cc3)C(F)(F)F)ccc2n1 Show InChI InChI=1S/C23H24F3N3O/c1-15(2)29(3)21-12-7-17-14-19(10-11-20(17)28-21)27-22(30)13-6-16-4-8-18(9-5-16)23(24,25)26/h4-5,7-12,14-15H,6,13H2,1-3H3,(H,27,30)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Stimulation of IP3-coupled mobilization of calcium in HEK293 cells expressing rat MCH-R1				Bioorg Med Chem Lett 16: 5270-4 (2006) Article DOI: 10.1016/j.bmcl.2006.08.006 BindingDB Entry DOI: 10.7270/Q2ZC82HP
					More data for this Ligand-Target Pair