BDBM50193702 CHEMBL217078::N-(2-(2-azabicyclo[2.2.1]heptan-2-yl)quinolin-6-yl)-3-(4-(trifluoromethyl)phenyl)propanamide

SMILES: FC(F)(F)c1ccc(CCC(=O)Nc2ccc3nc(ccc3c2)N2CC3CCC2C3)cc1

InChI Key: InChIKey=VMYOYPJHFIMQIY-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193702   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GPR24 (RAT)	BDBM50193702 (CHEMBL217078 | N-(2-(2-azabicyclo[2.2.1]heptan-2-y...) Show SMILES FC(F)(F)c1ccc(CCC(=O)Nc2ccc3nc(ccc3c2)N2CC3CCC2C3)cc1 |THB:18:23:29:27.26| Show InChI InChI=1S/C25H24F3N3O/c26-25(27,28)19-6-1-16(2-7-19)4-12-24(32)29-20-8-10-22-18(14-20)5-11-23(30-22)31-15-17-3-9-21(31)13-17/h1-2,5-8,10-11,14,17,21H,3-4,9,12-13,15H2,(H,29,32)	Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Stimulation of IP3-coupled mobilization of calcium in HEK293 cells expressing rat MCH-R1				Bioorg Med Chem Lett 16: 5270-4 (2006) Article DOI: 10.1016/j.bmcl.2006.08.006 BindingDB Entry DOI: 10.7270/Q2ZC82HP
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50193702 (CHEMBL217078 | N-(2-(2-azabicyclo[2.2.1]heptan-2-y...) Show SMILES FC(F)(F)c1ccc(CCC(=O)Nc2ccc3nc(ccc3c2)N2CC3CCC2C3)cc1 |THB:18:23:29:27.26| Show InChI InChI=1S/C25H24F3N3O/c26-25(27,28)19-6-1-16(2-7-19)4-12-24(32)29-20-8-10-22-18(14-20)5-11-23(30-22)31-15-17-3-9-21(31)13-17/h1-2,5-8,10-11,14,17,21H,3-4,9,12-13,15H2,(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of 125I-[Phe13,Tyr19]-MCH from human MCH-R1				Bioorg Med Chem Lett 16: 5270-4 (2006) Article DOI: 10.1016/j.bmcl.2006.08.006 BindingDB Entry DOI: 10.7270/Q2ZC82HP
					More data for this Ligand-Target Pair