BDBM50193872 1-((4-(4-chloro-2-(5-chloropyridin-2-ylcarbamoyl)phenylcarbamoyl)phenyl)(imino)methyl)piperidine-4-carboxylic acid::1-({4-[4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-phenylcarbamoyl]-phenyl}-imino-methyl)-piperidine-4-carboxylic acid::CHEMBL222012

SMILES: OC(=O)C1CCN(CC1)C(=N)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1

InChI Key: InChIKey=XVKPNRRLYPSIOE-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50193872   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50193872 (1-((4-(4-chloro-2-(5-chloropyridin-2-ylcarbamoyl)p...) Show SMILES OC(=O)C1CCN(CC1)C(=N)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C26H23Cl2N5O4/c27-18-5-7-21(20(13-18)25(35)32-22-8-6-19(28)14-30-22)31-24(34)16-3-1-15(2-4-16)23(29)33-11-9-17(10-12-33)26(36)37/h1-8,13-14,17,29H,9-12H2,(H,31,34)(H,36,37)(H,30,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Portola Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human ERG potassium channel expressed in HEK293 cells				Bioorg Med Chem Lett 16: 5507-12 (2006) Article DOI: 10.1016/j.bmcl.2006.08.039 BindingDB Entry DOI: 10.7270/Q2SF2X05
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50193872 (1-((4-(4-chloro-2-(5-chloropyridin-2-ylcarbamoyl)p...) Show SMILES OC(=O)C1CCN(CC1)C(=N)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C26H23Cl2N5O4/c27-18-5-7-21(20(13-18)25(35)32-22-8-6-19(28)14-30-22)31-24(34)16-3-1-15(2-4-16)23(29)33-11-9-17(10-12-33)26(36)37/h1-8,13-14,17,29H,9-12H2,(H,31,34)(H,36,37)(H,30,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Inhibition of human ERG by patch clamp assay				J Med Chem 53: 6243-74 (2010) Article DOI: 10.1021/jm100146h BindingDB Entry DOI: 10.7270/Q2CR5VBB
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50193872 (1-((4-(4-chloro-2-(5-chloropyridin-2-ylcarbamoyl)p...) Show SMILES OC(=O)C1CCN(CC1)C(=N)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1 Show InChI InChI=1S/C26H23Cl2N5O4/c27-18-5-7-21(20(13-18)25(35)32-22-8-6-19(28)14-30-22)31-24(34)16-3-1-15(2-4-16)23(29)33-11-9-17(10-12-33)26(36)37/h1-8,13-14,17,29H,9-12H2,(H,31,34)(H,36,37)(H,30,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of Factor 10a (unknown origin)				Bioorg Med Chem Lett 19: 2179-85 (2009) Article DOI: 10.1016/j.bmcl.2009.02.111 BindingDB Entry DOI: 10.7270/Q22Z15F5
					More data for this Ligand-Target Pair