BDBM50193887 7-(2,6-dimethylphenyl)-5,6-dimethyl-N-phenylbenzo[e][1,2,4]triazin-3-amine::CHEMBL221975::US8481536, 320

SMILES: Cc1cccc(C)c1-c1cc2nnc(Nc3ccccc3)nc2c(C)c1C

InChI Key: InChIKey=SUWQAWLRFPYRIH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193887   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50193887 (7-(2,6-dimethylphenyl)-5,6-dimethyl-N-phenylbenzo[...) Show SMILES Cc1cccc(C)c1-c1cc2nnc(Nc3ccccc3)nc2c(C)c1C |(25.05,-20.16,;23.71,-20.93,;22.38,-20.16,;21.05,-20.93,;21.05,-22.48,;22.39,-23.24,;22.39,-24.78,;23.71,-22.48,;25.04,-23.25,;26.37,-22.48,;27.71,-23.24,;29.04,-22.46,;30.38,-23.23,;30.39,-24.79,;31.73,-25.55,;31.73,-27.09,;30.41,-27.86,;30.41,-29.4,;31.75,-30.16,;33.08,-29.38,;33.07,-27.84,;29.05,-25.56,;27.71,-24.79,;26.37,-25.56,;26.37,-27.1,;25.04,-24.79,;23.71,-25.56,)| Show InChI InChI=1S/C23H22N4/c1-14-9-8-10-15(2)21(14)19-13-20-22(17(4)16(19)3)25-23(27-26-20)24-18-11-6-5-7-12-18/h5-13H,1-4H3,(H,24,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TargeGen, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Src kinase				Bioorg Med Chem Lett 16: 5546-50 (2006) Article DOI: 10.1016/j.bmcl.2006.08.035 BindingDB Entry DOI: 10.7270/Q2SN08MP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50193887 (7-(2,6-dimethylphenyl)-5,6-dimethyl-N-phenylbenzo[...) Show SMILES Cc1cccc(C)c1-c1cc2nnc(Nc3ccccc3)nc2c(C)c1C |(25.05,-20.16,;23.71,-20.93,;22.38,-20.16,;21.05,-20.93,;21.05,-22.48,;22.39,-23.24,;22.39,-24.78,;23.71,-22.48,;25.04,-23.25,;26.37,-22.48,;27.71,-23.24,;29.04,-22.46,;30.38,-23.23,;30.39,-24.79,;31.73,-25.55,;31.73,-27.09,;30.41,-27.86,;30.41,-29.4,;31.75,-30.16,;33.08,-29.38,;33.07,-27.84,;29.05,-25.56,;27.71,-24.79,;26.37,-25.56,;26.37,-27.1,;25.04,-24.79,;23.71,-25.56,)| Show InChI InChI=1S/C23H22N4/c1-14-9-8-10-15(2)21(14)19-13-20-22(17(4)16(19)3)25-23(27-26-20)24-18-11-6-5-7-12-18/h5-13H,1-4H3,(H,24,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	25
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
					More data for this Ligand-Target Pair