BDBM50193890 7-(2,6-dimethylphenyl)-5-methyl-N-(3-(4-methyl-2-propoxypiperazin-1-yl)phenyl)benzo[e][1,2,4]triazin-3-amine::CHEMBL375433

SMILES: CCCOC1CN(C)CCN1c1cccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)c1

InChI Key: InChIKey=BRMJAFDCQDQWRJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50193890   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50193890 (7-(2,6-dimethylphenyl)-5-methyl-N-(3-(4-methyl-2-p...) Show SMILES CCCOC1CN(C)CCN1c1cccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)c1 Show InChI InChI=1S/C30H36N6O/c1-6-15-37-27-19-35(5)13-14-36(27)25-12-8-11-24(18-25)31-30-32-29-22(4)16-23(17-26(29)33-34-30)28-20(2)9-7-10-21(28)3/h7-12,16-18,27H,6,13-15,19H2,1-5H3,(H,31,32,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TargeGen, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Src kinase				Bioorg Med Chem Lett 16: 5546-50 (2006) Article DOI: 10.1016/j.bmcl.2006.08.035 BindingDB Entry DOI: 10.7270/Q2SN08MP
					More data for this Ligand-Target Pair