BDBM50193894 7-(2,6-dimethylphenyl)-5-methyl-N-(3-(4-methylpiperazin-1-ylsulfonyl)phenyl)benzo[e][1,2,4]triazin-3-amine::CHEMBL436516::US8481536, 408

SMILES: CN1CCN(CC1)S(=O)(=O)c1cccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)c1

InChI Key: InChIKey=CLYYVIUHRKFXFH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193894   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50193894 (7-(2,6-dimethylphenyl)-5-methyl-N-(3-(4-methylpipe...) Show SMILES CN1CCN(CC1)S(=O)(=O)c1cccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)c1 Show InChI InChI=1S/C27H30N6O2S/c1-18-7-5-8-19(2)25(18)21-15-20(3)26-24(16-21)30-31-27(29-26)28-22-9-6-10-23(17-22)36(34,35)33-13-11-32(4)12-14-33/h5-10,15-17H,11-14H2,1-4H3,(H,28,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TargeGen, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Src kinase				Bioorg Med Chem Lett 16: 5546-50 (2006) Article DOI: 10.1016/j.bmcl.2006.08.035 BindingDB Entry DOI: 10.7270/Q2SN08MP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50193894 (7-(2,6-dimethylphenyl)-5-methyl-N-(3-(4-methylpipe...) Show SMILES CN1CCN(CC1)S(=O)(=O)c1cccc(Nc2nnc3cc(cc(C)c3n2)-c2c(C)cccc2C)c1 Show InChI InChI=1S/C27H30N6O2S/c1-18-7-5-8-19(2)25(18)21-15-20(3)26-24(16-21)30-31-27(29-26)28-22-9-6-10-23(17-22)36(34,35)33-13-11-32(4)12-14-33/h5-10,15-17H,11-14H2,1-4H3,(H,28,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	322	n/a	n/a	n/a	n/a	n/a	25
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
					More data for this Ligand-Target Pair