BDBM50193896 CHEMBL221739::N-(7-(2,6-dimethylphenyl)-5-methylbenzo[e][1,2,4]triazin-3-yl)acetamide::US8481536, 327

SMILES: CC(=O)Nc1nnc2cc(cc(C)c2n1)-c1c(C)cccc1C

InChI Key: InChIKey=KVHBEIUIQQKMED-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50193896   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50193896 (CHEMBL221739 | N-(7-(2,6-dimethylphenyl)-5-methylb...) Show SMILES CC(=O)Nc1nnc2cc(cc(C)c2n1)-c1c(C)cccc1C Show InChI InChI=1S/C18H18N4O/c1-10-6-5-7-11(2)16(10)14-8-12(3)17-15(9-14)21-22-18(20-17)19-13(4)23/h5-9H,1-4H3,(H,19,20,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TargeGen, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Src kinase				Bioorg Med Chem Lett 16: 5546-50 (2006) Article DOI: 10.1016/j.bmcl.2006.08.035 BindingDB Entry DOI: 10.7270/Q2SN08MP
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50193896 (CHEMBL221739 | N-(7-(2,6-dimethylphenyl)-5-methylb...) Show SMILES CC(=O)Nc1nnc2cc(cc(C)c2n1)-c1c(C)cccc1C Show InChI InChI=1S/C18H18N4O/c1-10-6-5-7-11(2)16(10)14-8-12(3)17-15(9-14)21-22-18(20-17)19-13(4)23/h5-9H,1-4H3,(H,19,20,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	25
TargeGen, Inc. US Patent					Assay Description Testing of inhibition of kinases in vitro using luciferase-based assay from KinaseGlo, Promega Corp.				US Patent US8481536 (2013) BindingDB Entry DOI: 10.7270/Q2GB22PZ
					More data for this Ligand-Target Pair