null
SMILES: Oc1ccc(CCN(CCc2ccccc2)CC2CCC2)cc1
InChI Key: InChIKey=NTAGTTSFZMQMGZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50194198 (CHEMBL3890511) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting | Bioorg Med Chem Lett 26: 4769-4774 (2016) Article DOI: 10.1016/j.bmcl.2016.08.031 BindingDB Entry DOI: 10.7270/Q2RJ4MD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50194198 (CHEMBL3890511) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 731 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting | Bioorg Med Chem Lett 26: 4769-4774 (2016) Article DOI: 10.1016/j.bmcl.2016.08.031 BindingDB Entry DOI: 10.7270/Q2RJ4MD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50194198 (CHEMBL3890511) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Displacement of [3H]pCl-DPDPE from human delta opioid receptor expressed in CHO cell membranes after 60 mins by liquid scintillation counting | Bioorg Med Chem Lett 26: 4769-4774 (2016) Article DOI: 10.1016/j.bmcl.2016.08.031 BindingDB Entry DOI: 10.7270/Q2RJ4MD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50194198 (CHEMBL3890511) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 109 | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Agonist activity at human kappa opioid receptor expressed in CHO cell membranes after 60 mins by [35S]GTPgammaS assay | Bioorg Med Chem Lett 26: 4769-4774 (2016) Article DOI: 10.1016/j.bmcl.2016.08.031 BindingDB Entry DOI: 10.7270/Q2RJ4MD9 | |||||||||||
More data for this Ligand-Target Pair |