BDBM50194269 (+/-)-3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-cis-6,11-dimethyl-N-[1,1'-biphenyl]-4-yl-2,6-methano-3-benzazocine-8-carboxamide::CHEMBL215760

SMILES: C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(=O)Nc1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=HBRATRYIPHBULI-YAALIPEISA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194269   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50194269 ((+/-)-3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-...) Show SMILES C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(=O)Nc1ccc(cc1)-c1ccccc1 |TLB:8:9:1:14.12.13,15:14:1:4.9.3| Show InChI InChI=1S/C31H34N2O/c1-21-29-19-25-10-11-26(18-28(25)31(21,2)16-17-33(29)20-22-8-9-22)30(34)32-27-14-12-24(13-15-27)23-6-4-3-5-7-23/h3-7,10-15,18,21-22,29H,8-9,16-17,19-20H2,1-2H3,(H,32,34)/t21-,29?,31-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rensselaer Polytechnic Institute Curated by ChEMBL					Assay Description Antagonist activity against human mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding				J Med Chem 49: 5635-9 (2006) Article DOI: 10.1021/jm060278n BindingDB Entry DOI: 10.7270/Q208663G
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50194269 ((+/-)-3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-...) Show SMILES C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(=O)Nc1ccc(cc1)-c1ccccc1 |TLB:8:9:1:14.12.13,15:14:1:4.9.3| Show InChI InChI=1S/C31H34N2O/c1-21-29-19-25-10-11-26(18-28(25)31(21,2)16-17-33(29)20-22-8-9-22)30(34)32-27-14-12-24(13-15-27)23-6-4-3-5-7-23/h3-7,10-15,18,21-22,29H,8-9,16-17,19-20H2,1-2H3,(H,32,34)/t21-,29?,31-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rensselaer Polytechnic Institute Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from human kappa opioid receptor expressed in CHO cells				J Med Chem 49: 5635-9 (2006) Article DOI: 10.1021/jm060278n BindingDB Entry DOI: 10.7270/Q208663G
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50194269 ((+/-)-3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-...) Show SMILES C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(=O)Nc1ccc(cc1)-c1ccccc1 |TLB:8:9:1:14.12.13,15:14:1:4.9.3| Show InChI InChI=1S/C31H34N2O/c1-21-29-19-25-10-11-26(18-28(25)31(21,2)16-17-33(29)20-22-8-9-22)30(34)32-27-14-12-24(13-15-27)23-6-4-3-5-7-23/h3-7,10-15,18,21-22,29H,8-9,16-17,19-20H2,1-2H3,(H,32,34)/t21-,29?,31-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rensselaer Polytechnic Institute Curated by ChEMBL					Assay Description Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells				J Med Chem 49: 5635-9 (2006) Article DOI: 10.1021/jm060278n BindingDB Entry DOI: 10.7270/Q208663G
					More data for this Ligand-Target Pair