BDBM50194284 5-(4-(4-(4-(3-fluorophenyl)oxazol-2-yl)phenoxy)phenoxy)-5-(2-methoxyethyl)pyrimidine-2,4,6(1H,3H,5H)-trione::CHEMBL222007

SMILES: COCCC1(Oc2ccc(Oc3ccc(cc3)-c3nc(co3)-c3cccc(F)c3)cc2)C(=O)NC(=O)NC1=O

InChI Key: InChIKey=VZODRLLXYBAWGB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50194284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50194284 (5-(4-(4-(4-(3-fluorophenyl)oxazol-2-yl)phenoxy)phe...) Show SMILES COCCC1(Oc2ccc(Oc3ccc(cc3)-c3nc(co3)-c3cccc(F)c3)cc2)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C28H22FN3O7/c1-36-14-13-28(25(33)31-27(35)32-26(28)34)39-22-11-9-21(10-12-22)38-20-7-5-17(6-8-20)24-30-23(16-37-24)18-3-2-4-19(29)15-18/h2-12,15-16H,13-14H2,1H3,(H2,31,32,33,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem Lett 16: 5822-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.066 BindingDB Entry DOI: 10.7270/Q27P8Z1R
					More data for this Ligand-Target Pair