BDBM50194302 5-(2-ethoxyethyl)-5-(4-(4-(4-(2-fluorophenyl)oxazol-2-yl)phenoxy)phenoxy)pyrimidine-2,4,6(1H,3H,5H)-trione::CHEMBL374915

SMILES: CCOCCC1(Oc2ccc(Oc3ccc(cc3)-c3nc(co3)-c3ccccc3F)cc2)C(=O)NC(=O)NC1=O

InChI Key: InChIKey=WKFZJKDVVULWLA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50194302   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50194302 (5-(2-ethoxyethyl)-5-(4-(4-(4-(2-fluorophenyl)oxazo...) Show SMILES CCOCCC1(Oc2ccc(Oc3ccc(cc3)-c3nc(co3)-c3ccccc3F)cc2)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C29H24FN3O7/c1-2-37-16-15-29(26(34)32-28(36)33-27(29)35)40-21-13-11-20(12-14-21)39-19-9-7-18(8-10-19)25-31-24(17-38-25)22-5-3-4-6-23(22)30/h3-14,17H,2,15-16H2,1H3,(H2,32,33,34,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.930	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem Lett 17: 6529-34 (2007) Article DOI: 10.1016/j.bmcl.2007.09.085 BindingDB Entry DOI: 10.7270/Q2ZW1KMR
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50194302 (5-(2-ethoxyethyl)-5-(4-(4-(4-(2-fluorophenyl)oxazo...) Show SMILES CCOCCC1(Oc2ccc(Oc3ccc(cc3)-c3nc(co3)-c3ccccc3F)cc2)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C29H24FN3O7/c1-2-37-16-15-29(26(34)32-28(36)33-27(29)35)40-21-13-11-20(12-14-21)39-19-9-7-18(8-10-19)25-31-24(17-38-25)22-5-3-4-6-23(22)30/h3-14,17H,2,15-16H2,1H3,(H2,32,33,34,35,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.930	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem Lett 16: 5822-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.066 BindingDB Entry DOI: 10.7270/Q27P8Z1R
					More data for this Ligand-Target Pair