BDBM50194310 5-(2-ethoxyethyl)-5-(4-(4-(3-phenylisoxazol-5-yl)phenoxy)phenoxy)pyrimidine-2,4,6(1H,3H,5H)-trione::CHEMBL220964

SMILES: CCOCCC1(Oc2ccc(Oc3ccc(cc3)-c3cc(no3)-c3ccccc3)cc2)C(=O)NC(=O)NC1=O

InChI Key: InChIKey=SDPYWOXUCQVWHK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50194310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50194310 (5-(2-ethoxyethyl)-5-(4-(4-(3-phenylisoxazol-5-yl)p...) Show SMILES CCOCCC1(Oc2ccc(Oc3ccc(cc3)-c3cc(no3)-c3ccccc3)cc2)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C29H25N3O7/c1-2-36-17-16-29(26(33)30-28(35)31-27(29)34)38-23-14-12-22(13-15-23)37-21-10-8-20(9-11-21)25-18-24(32-39-25)19-6-4-3-5-7-19/h3-15,18H,2,16-17H2,1H3,(H2,30,31,33,34,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem Lett 16: 5822-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.066 BindingDB Entry DOI: 10.7270/Q27P8Z1R
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