BDBM50194311 4-(4-(5-(2-ethoxyethyl)-2,4,6-trioxo-hexahydropyrimidin-5-yloxy)phenoxy)-N-phenylbenzamide::CHEMBL375667

SMILES: CCOCCC1(Oc2ccc(Oc3ccc(cc3)C(=O)Nc3ccccc3)cc2)C(=O)NC(=O)NC1=O

InChI Key: InChIKey=NWCAKMHOURFTPM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50194311   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM50194311 (4-(4-(5-(2-ethoxyethyl)-2,4,6-trioxo-hexahydropyri...) Show SMILES CCOCCC1(Oc2ccc(Oc3ccc(cc3)C(=O)Nc3ccccc3)cc2)C(=O)NC(=O)NC1=O Show InChI InChI=1S/C27H25N3O7/c1-2-35-17-16-27(24(32)29-26(34)30-25(27)33)37-22-14-12-21(13-15-22)36-20-10-8-18(9-11-20)23(31)28-19-6-4-3-5-7-19/h3-15H,2,16-17H2,1H3,(H,28,31)(H2,29,30,32,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.840	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Inhibition of MMP13				Bioorg Med Chem Lett 16: 5822-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.066 BindingDB Entry DOI: 10.7270/Q27P8Z1R
					More data for this Ligand-Target Pair