BDBM50194554 CHEMBL374438::N'-[3-(4-methyl-piperazin-1-ylmethyl)-2-phenyl-quinoline-4-carbonyl]-N-phenyl-hydrazinecarboxylic acid methyl ester

SMILES: COC(=O)N(NC(=O)c1c(CN2CCN(C)CC2)c(nc2ccccc12)-c1ccccc1)c1ccccc1

InChI Key: InChIKey=YSDZQWRVRDWYHN-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50194554   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50194554 (CHEMBL374438 | N'-[3-(4-methyl-piperazin-1-ylmethy...) Show SMILES COC(=O)N(NC(=O)c1c(CN2CCN(C)CC2)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H31N5O3/c1-33-17-19-34(20-18-33)21-25-27(29(36)32-35(30(37)38-2)23-13-7-4-8-14-23)24-15-9-10-16-26(24)31-28(25)22-11-5-3-6-12-22/h3-16H,17-21H2,1-2H3,(H,32,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of labeled MK499 from cloned hERG potassium channel expressed in HEK cells				Bioorg Med Chem Lett 16: 5752-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.085 BindingDB Entry DOI: 10.7270/Q2TD9X0S
					More data for this Ligand-Target Pair
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50194554 (CHEMBL374438 | N'-[3-(4-methyl-piperazin-1-ylmethy...) Show SMILES COC(=O)N(NC(=O)c1c(CN2CCN(C)CC2)c(nc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H31N5O3/c1-33-17-19-34(20-18-33)21-25-27(29(36)32-35(30(37)38-2)23-13-7-4-8-14-23)24-15-9-10-16-26(24)31-28(25)22-11-5-3-6-12-22/h3-16H,17-21H2,1-2H3,(H,32,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]neurokinin B from human cloned NK3 receptor expressed in CHO cells				Bioorg Med Chem Lett 16: 5752-6 (2006) Article DOI: 10.1016/j.bmcl.2006.08.085 BindingDB Entry DOI: 10.7270/Q2TD9X0S
					More data for this Ligand-Target Pair