BDBM50194623 (1S,5S,6R,E)-5-(hydroxymethyl)-1-methoxy-6-(6-methylhepta-2,5-dien-2-yl)bicyclo[3.1.0]hexan-2-one::CHEMBL213526::Fumarranol Analog, 8

SMILES: [#6]-[#8][C@@]12[#6](\[#6](-[#6])=[#6]\[#6]\[#6]=[#6](\[#6])-[#6])[C@]1([#6]-[#8])[#6]-[#6]-[#6]2=O

InChI Key: InChIKey=NTBXTHBAQMHZTL-QBJZEIPOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50194623   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM50194623 ((1S,5S,6R,E)-5-(hydroxymethyl)-1-methoxy-6-(6-meth...) Show SMILES [#6]-[#8][C@@]12[#6](\[#6](-[#6])=[#6]\[#6]\[#6]=[#6](\[#6])-[#6])[C@]1([#6]-[#8])[#6]-[#6]-[#6]2=O Show InChI InChI=1S/C16H24O3/c1-11(2)6-5-7-12(3)14-15(10-17)9-8-13(18)16(14,15)19-4/h6-7,14,17H,5,8-10H2,1-4H3/b12-7+/t14?,15-,16+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Johns Hopkins University School of Medicine Curated by ChEMBL					Assay Description Inhibition of human MetAP2				J Med Chem 49: 5645-8 (2006) Article DOI: 10.1021/jm060559v BindingDB Entry DOI: 10.7270/Q2PN959W
					More data for this Ligand-Target Pair
Methionine aminopeptidase (MetAP2) (Plasmodium falciparum)	BDBM50194623 ((1S,5S,6R,E)-5-(hydroxymethyl)-1-methoxy-6-(6-meth...) Show SMILES [#6]-[#8][C@@]12[#6](\[#6](-[#6])=[#6]\[#6]\[#6]=[#6](\[#6])-[#6])[C@]1([#6]-[#8])[#6]-[#6]-[#6]2=O Show InChI InChI=1S/C16H24O3/c1-11(2)6-5-7-12(3)14-15(10-17)9-8-13(18)16(14,15)19-4/h6-7,14,17H,5,8-10H2,1-4H3/b12-7+/t14?,15-,16+/m1/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Johns Hopkins School of Medicine					Assay Description Enzyme affinity assay using Fumarranol analogs with plasmodium falciparum methionine aminopeptidases (PfMetAPs).				Chem Biol 16: 193-202 (2009) Article DOI: 10.1016/j.chembiol.2009.01.006 BindingDB Entry DOI: 10.7270/Q2WS8RQ5
					More data for this Ligand-Target Pair