BDBM50194647 (2R)-1-[(2S,4R)-4-hydroxy-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-yl]carbonyl-N-(4-piperidinylethyl)pyrrolidine-2-carboxamide::CHEMBL211976

SMILES: O[C@@H]1C[C@H](N(C1)C(=O)CC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N1CCC[C@@H]1C(=O)NCCC1CCNCC1

InChI Key: InChIKey=KFVGSPFDTINYRJ-SXLOSVNLSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50194647   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50194647 ((2R)-1-[(2S,4R)-4-hydroxy-1-(3,3,3-triphenylpropan...) Show SMILES O[C@@H]1C[C@H](N(C1)C(=O)CC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N1CCC[C@@H]1C(=O)NCCC1CCNCC1 Show InChI InChI=1S/C38H46N4O4/c43-32-25-34(37(46)41-24-10-17-33(41)36(45)40-23-20-28-18-21-39-22-19-28)42(27-32)35(44)26-38(29-11-4-1-5-12-29,30-13-6-2-7-14-30)31-15-8-3-9-16-31/h1-9,11-16,28,32-34,39,43H,10,17-27H2,(H,40,45)/t32-,33-,34+/m1/s1	Reactome pathway KEGG DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human cloned M3 receptor expressed in CHO cells				J Med Chem 49: 5653-63 (2006) Article DOI: 10.1021/jm051205r BindingDB Entry DOI: 10.7270/Q2F76C6K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50194647 ((2R)-1-[(2S,4R)-4-hydroxy-1-(3,3,3-triphenylpropan...) Show SMILES O[C@@H]1C[C@H](N(C1)C(=O)CC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N1CCC[C@@H]1C(=O)NCCC1CCNCC1 Show InChI InChI=1S/C38H46N4O4/c43-32-25-34(37(46)41-24-10-17-33(41)36(45)40-23-20-28-18-21-39-22-19-28)42(27-32)35(44)26-38(29-11-4-1-5-12-29,30-13-6-2-7-14-30)31-15-8-3-9-16-31/h1-9,11-16,28,32-34,39,43H,10,17-27H2,(H,40,45)/t32-,33-,34+/m1/s1	Reactome pathway KEGG DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human cloned M4 receptor expressed in CHO cells				J Med Chem 49: 5653-63 (2006) Article DOI: 10.1021/jm051205r BindingDB Entry DOI: 10.7270/Q2F76C6K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50194647 ((2R)-1-[(2S,4R)-4-hydroxy-1-(3,3,3-triphenylpropan...) Show SMILES O[C@@H]1C[C@H](N(C1)C(=O)CC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N1CCC[C@@H]1C(=O)NCCC1CCNCC1 Show InChI InChI=1S/C38H46N4O4/c43-32-25-34(37(46)41-24-10-17-33(41)36(45)40-23-20-28-18-21-39-22-19-28)42(27-32)35(44)26-38(29-11-4-1-5-12-29,30-13-6-2-7-14-30)31-15-8-3-9-16-31/h1-9,11-16,28,32-34,39,43H,10,17-27H2,(H,40,45)/t32-,33-,34+/m1/s1	PDB GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human cloned M2 receptor expressed in CHO cells				J Med Chem 49: 5653-63 (2006) Article DOI: 10.1021/jm051205r BindingDB Entry DOI: 10.7270/Q2F76C6K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50194647 ((2R)-1-[(2S,4R)-4-hydroxy-1-(3,3,3-triphenylpropan...) Show SMILES O[C@@H]1C[C@H](N(C1)C(=O)CC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N1CCC[C@@H]1C(=O)NCCC1CCNCC1 Show InChI InChI=1S/C38H46N4O4/c43-32-25-34(37(46)41-24-10-17-33(41)36(45)40-23-20-28-18-21-39-22-19-28)42(27-32)35(44)26-38(29-11-4-1-5-12-29,30-13-6-2-7-14-30)31-15-8-3-9-16-31/h1-9,11-16,28,32-34,39,43H,10,17-27H2,(H,40,45)/t32-,33-,34+/m1/s1	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human cloned M1 receptor expressed in CHO cells				J Med Chem 49: 5653-63 (2006) Article DOI: 10.1021/jm051205r BindingDB Entry DOI: 10.7270/Q2F76C6K
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50194647 ((2R)-1-[(2S,4R)-4-hydroxy-1-(3,3,3-triphenylpropan...) Show SMILES O[C@@H]1C[C@H](N(C1)C(=O)CC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)N1CCC[C@@H]1C(=O)NCCC1CCNCC1 Show InChI InChI=1S/C38H46N4O4/c43-32-25-34(37(46)41-24-10-17-33(41)36(45)40-23-20-28-18-21-39-22-19-28)42(27-32)35(44)26-38(29-11-4-1-5-12-29,30-13-6-2-7-14-30)31-15-8-3-9-16-31/h1-9,11-16,28,32-34,39,43H,10,17-27H2,(H,40,45)/t32-,33-,34+/m1/s1	Reactome pathway KEGG DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of [3H]NMS binding to human cloned M5 receptor expressed in CHO cells				J Med Chem 49: 5653-63 (2006) Article DOI: 10.1021/jm051205r BindingDB Entry DOI: 10.7270/Q2F76C6K
					More data for this Ligand-Target Pair