BDBM50194965 (S)-2-methoxy-2-methyl-3-(6-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)pyridin-3-yl)propanoic acid::CHEMBL222117

SMILES: CO[C@@](C)(Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)nc1)C(O)=O

InChI Key: InChIKey=QQJHRCMKKXNPSH-QFIPXVFZSA-N

Data: 1 KI  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50194965   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50194965 ((S)-2-methoxy-2-methyl-3-(6-(2-(5-methyl-2-phenylo...) Show SMILES CO[C@@](C)(Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)nc1)C(O)=O Show InChI InChI=1S/C22H24N2O5/c1-15-18(24-20(29-15)17-7-5-4-6-8-17)11-12-28-19-10-9-16(14-23-19)13-22(2,27-3)21(25)26/h4-10,14H,11-13H2,1-3H3,(H,25,26)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global R&D Curated by ChEMBL					Assay Description Displacement of radiolabeled darglitazone from human PPAR gamma by SPA binding assay				Bioorg Med Chem Lett 16: 6120-3 (2006) Article DOI: 10.1016/j.bmcl.2006.08.110 BindingDB Entry DOI: 10.7270/Q20Z72XV
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50194965 ((S)-2-methoxy-2-methyl-3-(6-(2-(5-methyl-2-phenylo...) Show SMILES CO[C@@](C)(Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)nc1)C(O)=O Show InChI InChI=1S/C22H24N2O5/c1-15-18(24-20(29-15)17-7-5-4-6-8-17)11-12-28-19-10-9-16(14-23-19)13-22(2,27-3)21(25)26/h4-10,14H,11-13H2,1-3H3,(H,25,26)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Pfizer Global R&D Curated by ChEMBL					Assay Description Agonist activity at human PPAR gamma in a HepG2 cells by PPAR-GAL4 transactivation assay				Bioorg Med Chem Lett 16: 6120-3 (2006) Article DOI: 10.1016/j.bmcl.2006.08.110 BindingDB Entry DOI: 10.7270/Q20Z72XV
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50194965 ((S)-2-methoxy-2-methyl-3-(6-(2-(5-methyl-2-phenylo...) Show SMILES CO[C@@](C)(Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)nc1)C(O)=O Show InChI InChI=1S/C22H24N2O5/c1-15-18(24-20(29-15)17-7-5-4-6-8-17)11-12-28-19-10-9-16(14-23-19)13-22(2,27-3)21(25)26/h4-10,14H,11-13H2,1-3H3,(H,25,26)/t22-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	570	n/a	n/a	n/a	n/a
Pfizer Global R&D Curated by ChEMBL					Assay Description Displacement of radiolabeled GW2331 from human PPAR alpha by SPA binding assay				Bioorg Med Chem Lett 16: 6120-3 (2006) Article DOI: 10.1016/j.bmcl.2006.08.110 BindingDB Entry DOI: 10.7270/Q20Z72XV
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50194965 ((S)-2-methoxy-2-methyl-3-(6-(2-(5-methyl-2-phenylo...) Show SMILES CO[C@@](C)(Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)nc1)C(O)=O Show InChI InChI=1S/C22H24N2O5/c1-15-18(24-20(29-15)17-7-5-4-6-8-17)11-12-28-19-10-9-16(14-23-19)13-22(2,27-3)21(25)26/h4-10,14H,11-13H2,1-3H3,(H,25,26)/t22-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	111	n/a	n/a	n/a	n/a
Pfizer Global R&D Curated by ChEMBL					Assay Description Agonist activity at human PPAR alpha in a HepG2 cells by PPAR-GAL4 transactivation assay				Bioorg Med Chem Lett 16: 6120-3 (2006) Article DOI: 10.1016/j.bmcl.2006.08.110 BindingDB Entry DOI: 10.7270/Q20Z72XV
					More data for this Ligand-Target Pair