BDBM50194972 1-((6-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)pyridin-3-yl)methyl)cyclopropanecarboxylic acid::CHEMBL219005
SMILES: Cc1oc(nc1CCOc1ccc(CC2(CC2)C(O)=O)cn1)-c1ccccc1
InChI Key: InChIKey=AFJDPZQOARQRHU-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor (Homo sapiens (Human)) | BDBM50194972 (1-((6-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)pyri...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 7.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global R&D Curated by ChEMBL | Assay Description Displacement of radiolabeled darglitazone from human PPAR gamma by SPA binding assay | Bioorg Med Chem Lett 16: 6120-3 (2006) Article DOI: 10.1016/j.bmcl.2006.08.110 BindingDB Entry DOI: 10.7270/Q20Z72XV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human)) | BDBM50194972 (1-((6-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)pyri...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.15E+3 | n/a | n/a | n/a | n/a |
Pfizer Global R&D Curated by ChEMBL | Assay Description Agonist activity at human PPAR alpha in a HepG2 cells by PPAR-GAL4 transactivation assay | Bioorg Med Chem Lett 16: 6120-3 (2006) Article DOI: 10.1016/j.bmcl.2006.08.110 BindingDB Entry DOI: 10.7270/Q20Z72XV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor (Homo sapiens (Human)) | BDBM50194972 (1-((6-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)pyri...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.01E+3 | n/a | n/a | n/a | n/a |
Pfizer Global R&D Curated by ChEMBL | Assay Description Agonist activity at human PPAR gamma in a HepG2 cells by PPAR-GAL4 transactivation assay | Bioorg Med Chem Lett 16: 6120-3 (2006) Article DOI: 10.1016/j.bmcl.2006.08.110 BindingDB Entry DOI: 10.7270/Q20Z72XV | |||||||||||
More data for this Ligand-Target Pair |