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SMILES: CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)c(N)c1)C(=O)Oc1ccccc1

InChI Key: InChIKey=BLIPFJSFYMJJHD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50195366   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50195366
PNG
(CHEMBL3906985)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)c(N)c1)C(=O)Oc1ccccc1
Show InChI InChI=1S/C25H25FN4O3/c1-29-11-13-30(14-12-29)23-10-8-18(25(32)33-19-5-3-2-4-6-19)16-22(23)28-24(31)17-7-9-20(26)21(27)15-17/h2-10,15-16H,11-14,27H2,1H3,(H,28,31)
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>20n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay

Bioorg Med Chem 24: 6109-6118 (2016)


Article DOI: 10.1016/j.bmc.2016.09.073
BindingDB Entry DOI: 10.7270/Q2F47R4K
More data for this
Ligand-Target Pair