BDBM50195370 CHEMBL3936042

SMILES: CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)c(C)c1Cl)C(O)=O

InChI Key: InChIKey=AYROZPQFRORZAA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50195370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50195370 (CHEMBL3936042) Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)c(C)c1Cl)C(O)=O Show InChI InChI=1S/C20H21ClFN3O3/c1-12-15(22)5-4-14(18(12)21)19(26)23-16-11-13(20(27)28)3-6-17(16)25-9-7-24(2)8-10-25/h3-6,11H,7-10H2,1-2H3,(H,23,26)(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem 24: 6109-6118 (2016) Article DOI: 10.1016/j.bmc.2016.09.073 BindingDB Entry DOI: 10.7270/Q2F47R4K
					More data for this Ligand-Target Pair