BDBM50195377 (4'-{[[1-(3-methyl-butyl)-piperidin-4-yl]-(4-pentyl-benzoyl)-amino]-methyl}-biphenyl-4-yl)-acetic acid methyl ester::CHEMBL375124
SMILES: CCCCCc1ccc(cc1)C(=O)N(Cc1ccc(cc1)-c1ccc(CC(=O)OC)cc1)C1CCN(CCC(C)C)CC1
InChI Key: InChIKey=ALYUYVFLAGJFDX-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Plasmepsin 2 (Plasmodium falciparum) | BDBM50195377 ((4'-{[[1-(3-methyl-butyl)-piperidin-4-yl]-(4-penty...) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Actelion Pharmaceuticals Ltd Curated by ChEMBL | Assay Description Inhibition of PM2 by FRET assay | Bioorg Med Chem Lett 16: 6194-9 (2006) Article DOI: 10.1016/j.bmcl.2006.09.027 BindingDB Entry DOI: 10.7270/Q2QJ7GZN | |||||||||||
More data for this Ligand-Target Pair |