BDBM50195428 CHEMBL3938878

SMILES: COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2ccc(F)c(N)c2)c1

InChI Key: InChIKey=YCXCGHRJLIOJRZ-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50195428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 (WDR5) (Homo sapiens (Human))	BDBM50195428 (CHEMBL3938878) Show SMILES COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2ccc(F)c(N)c2)c1 Show InChI InChI=1S/C20H23FN4O3/c1-24-7-9-25(10-8-24)18-6-4-14(20(27)28-2)12-17(18)23-19(26)13-3-5-15(21)16(22)11-13/h3-6,11-12H,7-10,22H2,1-2H3,(H,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>20	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of C-terminal 5-FAM-ARTEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay				Bioorg Med Chem 24: 6109-6118 (2016) Article DOI: 10.1016/j.bmc.2016.09.073 BindingDB Entry DOI: 10.7270/Q2F47R4K
					More data for this Ligand-Target Pair