BDBM50195450 2-(4-((4,6-dioxo-2-thioxo-tetrahydropyrimidin-5(6H)-ylidene)methyl)phenoxy)acetamide::CHEMBL220169
SMILES: [#7]-[#6](=O)-[#6]-[#8]-c1ccc(\[#6]=[#6]-2\[#6](=O)-[#7]-[#6](=S)-[#7]-[#6]-2=O)cc1
InChI Key: InChIKey=LERBSTKHDLUSPN-UHFFFAOYSA-N
Data: 1 Kd
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 1 (Homo sapiens (Human)) | BDBM50195450 (2-(4-((4,6-dioxo-2-thioxo-tetrahydropyrimidin-5(6H...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a |
University of Maryland Curated by ChEMBL | Assay Description Binding affinity to ERK2 by fluorescence quenching | Bioorg Med Chem Lett 16: 6281-7 (2006) Article DOI: 10.1016/j.bmcl.2006.09.038 BindingDB Entry DOI: 10.7270/Q2G160GV | |||||||||||
More data for this Ligand-Target Pair |