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BDBM50195527 CHEMBL387001::N-cycloheptyl-1-(p-fluorobenzyl)-7-methyl-1,8-naphthyridin-4(1H)-on-3-carboxamide

SMILES: Cc1ccc2c(n1)n(Cc1ccc(F)cc1)cc(C(=O)NC1CCCCCC1)c2=O

InChI Key: InChIKey=VQCHDSLTNRITFJ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195527   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(MOUSE)
BDBM50195527
PNG
(CHEMBL387001 | N-cycloheptyl-1-(p-fluorobenzyl)-7-...)
Show SMILES Cc1ccc2c(n1)n(Cc1ccc(F)cc1)cc(C(=O)NC1CCCCCC1)c2=O
Show InChI InChI=1S/C24H26FN3O2/c1-16-8-13-20-22(29)21(24(30)27-19-6-4-2-3-5-7-19)15-28(23(20)26-16)14-17-9-11-18(25)12-10-17/h8-13,15,19H,2-7,14H2,1H3,(H,27,30)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB2 receptor in DBA/J2 mouse spleen


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Mus musculus (Mouse))
BDBM50195527
PNG
(CHEMBL387001 | N-cycloheptyl-1-(p-fluorobenzyl)-7-...)
Show SMILES Cc1ccc2c(n1)n(Cc1ccc(F)cc1)cc(C(=O)NC1CCCCCC1)c2=O
Show InChI InChI=1S/C24H26FN3O2/c1-16-8-13-20-22(29)21(24(30)27-19-6-4-2-3-5-7-19)15-28(23(20)26-16)14-17-9-11-18(25)12-10-17/h8-13,15,19H,2-7,14H2,1H3,(H,27,30)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
4.30n/an/an/an/an/an/an/an/a



Universit£ di Pisa

Curated by ChEMBL


Assay Description
Displacement of [3H]CP-55940 from CB1 receptor in DBA/J2 mouse brain


J Med Chem 49: 5947-57 (2006)


Article DOI: 10.1021/jm0603466
BindingDB Entry DOI: 10.7270/Q2DB82N5
More data for this
Ligand-Target Pair