BDBM50195606 CHEMBL214837::N-hydroxy-6-(3,4-dihydro-4-oxo-6-(1,1-diphenylmethyl)-2-pyrimidinylthio)hexanamide

SMILES: ONC(=O)CCCCCSc1nc(cc(=O)[nH]1)C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=ZMIRRXWAPLJEMZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase HD1B (Zea mays)	BDBM50195606 (CHEMBL214837 | N-hydroxy-6-(3,4-dihydro-4-oxo-6-(1...) Show SMILES ONC(=O)CCCCCSc1nc(cc(=O)[nH]1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25N3O3S/c27-20(26-29)14-8-3-9-15-30-23-24-19(16-21(28)25-23)22(17-10-4-1-5-11-17)18-12-6-2-7-13-18/h1-2,4-7,10-13,16,22,29H,3,8-9,14-15H2,(H,26,27)(H,24,25,28)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of maize HD1B				J Med Chem 49: 6046-56 (2006) Article DOI: 10.1021/jm0605536 BindingDB Entry DOI: 10.7270/Q2Z31Z9B
					More data for this Ligand-Target Pair
Histone deacetylase HD2 (Zea mays)	BDBM50195606 (CHEMBL214837 | N-hydroxy-6-(3,4-dihydro-4-oxo-6-(1...) Show SMILES ONC(=O)CCCCCSc1nc(cc(=O)[nH]1)C(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25N3O3S/c27-20(26-29)14-8-3-9-15-30-23-24-19(16-21(28)25-23)22(17-10-4-1-5-11-17)18-12-6-2-7-13-18/h1-2,4-7,10-13,16,22,29H,3,8-9,14-15H2,(H,26,27)(H,24,25,28)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of maize HD2				J Med Chem 49: 6046-56 (2006) Article DOI: 10.1021/jm0605536 BindingDB Entry DOI: 10.7270/Q2Z31Z9B
					More data for this Ligand-Target Pair