BDBM50195610 CHEMBL216065::N-hydroxy-8-(3,4-dihydro-4-oxo-6-phenethyl-2-pyrimidinylthio)octanamide

SMILES: ONC(=O)CCCCCCCSc1nc(CCc2ccccc2)cc(=O)[nH]1

InChI Key: InChIKey=ALQKGXUYGGUXKZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195610   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase HD1B (Zea mays)	BDBM50195610 (CHEMBL216065 | N-hydroxy-8-(3,4-dihydro-4-oxo-6-ph...) Show SMILES ONC(=O)CCCCCCCSc1nc(CCc2ccccc2)cc(=O)[nH]1 Show InChI InChI=1S/C20H27N3O3S/c24-18(23-26)11-7-2-1-3-8-14-27-20-21-17(15-19(25)22-20)13-12-16-9-5-4-6-10-16/h4-6,9-10,15,26H,1-3,7-8,11-14H2,(H,23,24)(H,21,22,25)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of maize HD1B				J Med Chem 49: 6046-56 (2006) Article DOI: 10.1021/jm0605536 BindingDB Entry DOI: 10.7270/Q2Z31Z9B
					More data for this Ligand-Target Pair
Histone deacetylase HD2 (Zea mays)	BDBM50195610 (CHEMBL216065 | N-hydroxy-8-(3,4-dihydro-4-oxo-6-ph...) Show SMILES ONC(=O)CCCCCCCSc1nc(CCc2ccccc2)cc(=O)[nH]1 Show InChI InChI=1S/C20H27N3O3S/c24-18(23-26)11-7-2-1-3-8-14-27-20-21-17(15-19(25)22-20)13-12-16-9-5-4-6-10-16/h4-6,9-10,15,26H,1-3,7-8,11-14H2,(H,23,24)(H,21,22,25)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of maize HD2				J Med Chem 49: 6046-56 (2006) Article DOI: 10.1021/jm0605536 BindingDB Entry DOI: 10.7270/Q2Z31Z9B
					More data for this Ligand-Target Pair