BDBM50195611 CHEMBL216118::N-hydroxy-4-(3,4-dihydro-4-oxo-6-phenethyl-2-pyrimidinylthio)butanamide

SMILES: ONC(=O)CCCSc1nc(CCc2ccccc2)cc(=O)[nH]1

InChI Key: InChIKey=XEAPOFNXOHZEMR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase HD1B (Zea mays)	BDBM50195611 (CHEMBL216118 | N-hydroxy-4-(3,4-dihydro-4-oxo-6-ph...) Show SMILES ONC(=O)CCCSc1nc(CCc2ccccc2)cc(=O)[nH]1 Show InChI InChI=1S/C16H19N3O3S/c20-14(19-22)7-4-10-23-16-17-13(11-15(21)18-16)9-8-12-5-2-1-3-6-12/h1-3,5-6,11,22H,4,7-10H2,(H,19,20)(H,17,18,21)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of maize HD1B				J Med Chem 49: 6046-56 (2006) Article DOI: 10.1021/jm0605536 BindingDB Entry DOI: 10.7270/Q2Z31Z9B
					More data for this Ligand-Target Pair
Histone deacetylase HD2 (Zea mays)	BDBM50195611 (CHEMBL216118 | N-hydroxy-4-(3,4-dihydro-4-oxo-6-ph...) Show SMILES ONC(=O)CCCSc1nc(CCc2ccccc2)cc(=O)[nH]1 Show InChI InChI=1S/C16H19N3O3S/c20-14(19-22)7-4-10-23-16-17-13(11-15(21)18-16)9-8-12-5-2-1-3-6-12/h1-3,5-6,11,22H,4,7-10H2,(H,19,20)(H,17,18,21)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of maize HD2				J Med Chem 49: 6046-56 (2006) Article DOI: 10.1021/jm0605536 BindingDB Entry DOI: 10.7270/Q2Z31Z9B
					More data for this Ligand-Target Pair