BDBM50195615 CHEMBL218348::N-hydroxy-3-(3,4-dihydro-6-benzyl-4-oxopyrimidin-2-ylthio)methylcinnamylamide

SMILES: ONC(=O)C=Cc1cccc(CSc2nc(Cc3ccccc3)cc(=O)[nH]2)c1

InChI Key: InChIKey=BMMFOHWVLAPQSW-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50195615   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase HD2 (Zea mays)	BDBM50195615 (CHEMBL218348 | N-hydroxy-3-(3,4-dihydro-6-benzyl-4...) Show SMILES ONC(=O)C=Cc1cccc(CSc2nc(Cc3ccccc3)cc(=O)[nH]2)c1 |w:5.5| Show InChI InChI=1S/C21H19N3O3S/c25-19(24-27)10-9-16-7-4-8-17(11-16)14-28-21-22-18(13-20(26)23-21)12-15-5-2-1-3-6-15/h1-11,13,27H,12,14H2,(H,24,25)(H,22,23,26)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of maize HD2				J Med Chem 49: 6046-56 (2006) Article DOI: 10.1021/jm0605536 BindingDB Entry DOI: 10.7270/Q2Z31Z9B
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Mus musculus (Mouse))	BDBM50195615 (CHEMBL218348 | N-hydroxy-3-(3,4-dihydro-6-benzyl-4...) Show SMILES ONC(=O)C=Cc1cccc(CSc2nc(Cc3ccccc3)cc(=O)[nH]2)c1 |w:5.5| Show InChI InChI=1S/C21H19N3O3S/c25-19(24-27)10-9-16-7-4-8-17(11-16)14-28-21-22-18(13-20(26)23-21)12-15-5-2-1-3-6-15/h1-11,13,27H,12,14H2,(H,24,25)(H,22,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of mouse HDAC1				J Med Chem 49: 6046-56 (2006) Article DOI: 10.1021/jm0605536 BindingDB Entry DOI: 10.7270/Q2Z31Z9B
					More data for this Ligand-Target Pair
Histone deacetylase HD1B (Zea mays)	BDBM50195615 (CHEMBL218348 | N-hydroxy-3-(3,4-dihydro-6-benzyl-4...) Show SMILES ONC(=O)C=Cc1cccc(CSc2nc(Cc3ccccc3)cc(=O)[nH]2)c1 |w:5.5| Show InChI InChI=1S/C21H19N3O3S/c25-19(24-27)10-9-16-7-4-8-17(11-16)14-28-21-22-18(13-20(26)23-21)12-15-5-2-1-3-6-15/h1-11,13,27H,12,14H2,(H,24,25)(H,22,23,26)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of maize HD1B				J Med Chem 49: 6046-56 (2006) Article DOI: 10.1021/jm0605536 BindingDB Entry DOI: 10.7270/Q2Z31Z9B
					More data for this Ligand-Target Pair