BDBM50195822 ({[({[(2R,3S,4R,5R)-5-(6,7-difluoro-1-oxo-1,2-dihydroisoquinolin-2-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid::CHEMBL391663

SMILES: O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc2cc(F)c(F)cc2c1=O

InChI Key: InChIKey=UVFKSFDIWKHRJL-HKUMRIAESA-N

Data: 4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50195822   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purinergic receptor P2Y2 (Homo sapiens (Human))	BDBM50195822 (({[({[(2R,3S,4R,5R)-5-(6,7-difluoro-1-oxo-1,2-dihy...) Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc2cc(F)c(F)cc2c1=O |w:13.14,9.10| Show InChI InChI=1S/C14H16F2NO14P3/c15-8-3-6-1-2-17(13(20)7(6)4-9(8)16)14-12(19)11(18)10(29-14)5-28-33(24,25)31-34(26,27)30-32(21,22)23/h1-4,10-12,14,18-19H,5H2,(H,24,25)(H,26,27)(H2,21,22,23)/t10-,11-,12-,14-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
UCB-Group Curated by ChEMBL					Assay Description Agonist activity at human P2Y2 receptor expressed in human 1321N1 by FLIPR assay				Bioorg Med Chem Lett 17: 562-5 (2007) Article DOI: 10.1016/j.bmcl.2006.09.017 BindingDB Entry DOI: 10.7270/Q2CC11JS
					More data for this Ligand-Target Pair
Pyrimidinergic receptor P2Y6 (Homo sapiens (Human))	BDBM50195822 (({[({[(2R,3S,4R,5R)-5-(6,7-difluoro-1-oxo-1,2-dihy...) Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc2cc(F)c(F)cc2c1=O |w:13.14,9.10| Show InChI InChI=1S/C14H16F2NO14P3/c15-8-3-6-1-2-17(13(20)7(6)4-9(8)16)14-12(19)11(18)10(29-14)5-28-33(24,25)31-34(26,27)30-32(21,22)23/h1-4,10-12,14,18-19H,5H2,(H,24,25)(H,26,27)(H2,21,22,23)/t10-,11-,12-,14-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
UCB-Group Curated by ChEMBL					Assay Description Agonist activity at human cloned P2Y6 receptor expressed in human 1321N1 by FLIPR assay				Bioorg Med Chem Lett 17: 562-5 (2007) Article DOI: 10.1016/j.bmcl.2006.09.017 BindingDB Entry DOI: 10.7270/Q2CC11JS
					More data for this Ligand-Target Pair
Purinergic receptor P2Y1 (Homo sapiens (Human))	BDBM50195822 (({[({[(2R,3S,4R,5R)-5-(6,7-difluoro-1-oxo-1,2-dihy...) Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc2cc(F)c(F)cc2c1=O |w:13.14,9.10| Show InChI InChI=1S/C14H16F2NO14P3/c15-8-3-6-1-2-17(13(20)7(6)4-9(8)16)14-12(19)11(18)10(29-14)5-28-33(24,25)31-34(26,27)30-32(21,22)23/h1-4,10-12,14,18-19H,5H2,(H,24,25)(H,26,27)(H2,21,22,23)/t10-,11-,12-,14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
UCB-Group Curated by ChEMBL					Assay Description Agonist activity at human cloned P2Y1 receptor expressed in human 1321N1 by FLIPR assay				Bioorg Med Chem Lett 17: 562-5 (2007) Article DOI: 10.1016/j.bmcl.2006.09.017 BindingDB Entry DOI: 10.7270/Q2CC11JS
					More data for this Ligand-Target Pair
Pyrimidinergic receptor P2Y4 (Homo sapiens (Human))	BDBM50195822 (({[({[(2R,3S,4R,5R)-5-(6,7-difluoro-1-oxo-1,2-dihy...) Show SMILES O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)n1ccc2cc(F)c(F)cc2c1=O |w:13.14,9.10| Show InChI InChI=1S/C14H16F2NO14P3/c15-8-3-6-1-2-17(13(20)7(6)4-9(8)16)14-12(19)11(18)10(29-14)5-28-33(24,25)31-34(26,27)30-32(21,22)23/h1-4,10-12,14,18-19H,5H2,(H,24,25)(H,26,27)(H2,21,22,23)/t10-,11-,12-,14-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
UCB-Group Curated by ChEMBL					Assay Description Agonist activity at human cloned P2Y4 receptor expressed in human 1321N1 by FLIPR assay				Bioorg Med Chem Lett 17: 562-5 (2007) Article DOI: 10.1016/j.bmcl.2006.09.017 BindingDB Entry DOI: 10.7270/Q2CC11JS
					More data for this Ligand-Target Pair