BDBM50196234 8-methyl-5,6,7,8,9,10,15,16-octahydroindolo[3,2-g][4]benzazacycloundecine::CHEMBL216258

SMILES: CN1CCCc2ccccc2Cc2[nH]c3ccccc3c2CC1

InChI Key: InChIKey=SJSQVUBCTSCTIM-UHFFFAOYSA-N

Data: 10 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50196234   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50196234 (8-methyl-5,6,7,8,9,10,15,16-octahydroindolo[3,2-g]...) Show SMILES CN1CCCc2ccccc2Cc2[nH]c3ccccc3c2CC1 Show InChI InChI=1S/C21H24N2/c1-23-13-6-9-16-7-2-3-8-17(16)15-21-19(12-14-23)18-10-4-5-11-20(18)22-21/h2-5,7-8,10-11,22H,6,9,12-15H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from human D5 dopamine receptor expressed in HEK293 cells				J Med Chem 49: 6408-11 (2006) Article DOI: 10.1021/jm060213k BindingDB Entry DOI: 10.7270/Q2GT5MTB
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50196234 (8-methyl-5,6,7,8,9,10,15,16-octahydroindolo[3,2-g]...) Show SMILES CN1CCCc2ccccc2Cc2[nH]c3ccccc3c2CC1 Show InChI InChI=1S/C21H24N2/c1-23-13-6-9-16-7-2-3-8-17(16)15-21-19(12-14-23)18-10-4-5-11-20(18)22-21/h2-5,7-8,10-11,22H,6,9,12-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Activity at human D2L dopamine receptor expressed in HEK293 cells by calcium fluorescence assay				J Med Chem 49: 6408-11 (2006) Article DOI: 10.1021/jm060213k BindingDB Entry DOI: 10.7270/Q2GT5MTB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50196234 (8-methyl-5,6,7,8,9,10,15,16-octahydroindolo[3,2-g]...) Show SMILES CN1CCCc2ccccc2Cc2[nH]c3ccccc3c2CC1 Show InChI InChI=1S/C21H24N2/c1-23-13-6-9-16-7-2-3-8-17(16)15-21-19(12-14-23)18-10-4-5-11-20(18)22-21/h2-5,7-8,10-11,22H,6,9,12-15H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.04	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human cloned dopamine D1 receptor				Bioorg Med Chem Lett 18: 3809-13 (2008) Article DOI: 10.1016/j.bmcl.2008.04.081 BindingDB Entry DOI: 10.7270/Q23F4QWW
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50196234 (8-methyl-5,6,7,8,9,10,15,16-octahydroindolo[3,2-g]...) Show SMILES CN1CCCc2ccccc2Cc2[nH]c3ccccc3c2CC1 Show InChI InChI=1S/C21H24N2/c1-23-13-6-9-16-7-2-3-8-17(16)15-21-19(12-14-23)18-10-4-5-11-20(18)22-21/h2-5,7-8,10-11,22H,6,9,12-15H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH 23390 from human D1 dopamine receptor expressed in HEK293 cells				J Med Chem 49: 6408-11 (2006) Article DOI: 10.1021/jm060213k BindingDB Entry DOI: 10.7270/Q2GT5MTB
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50196234 (8-methyl-5,6,7,8,9,10,15,16-octahydroindolo[3,2-g]...) Show SMILES CN1CCCc2ccccc2Cc2[nH]c3ccccc3c2CC1 Show InChI InChI=1S/C21H24N2/c1-23-13-6-9-16-7-2-3-8-17(16)15-21-19(12-14-23)18-10-4-5-11-20(18)22-21/h2-5,7-8,10-11,22H,6,9,12-15H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Activity at human D5 dopamine receptor expressed in HEK293 cells by calcium fluorescence assay				J Med Chem 49: 6408-11 (2006) Article DOI: 10.1021/jm060213k BindingDB Entry DOI: 10.7270/Q2GT5MTB
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50196234 (8-methyl-5,6,7,8,9,10,15,16-octahydroindolo[3,2-g]...) Show SMILES CN1CCCc2ccccc2Cc2[nH]c3ccccc3c2CC1 Show InChI InChI=1S/C21H24N2/c1-23-13-6-9-16-7-2-3-8-17(16)15-21-19(12-14-23)18-10-4-5-11-20(18)22-21/h2-5,7-8,10-11,22H,6,9,12-15H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Activity at human D1 dopamine receptor expressed in HEK293 cells by calcium fluorescence assay				J Med Chem 49: 6408-11 (2006) Article DOI: 10.1021/jm060213k BindingDB Entry DOI: 10.7270/Q2GT5MTB
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50196234 (8-methyl-5,6,7,8,9,10,15,16-octahydroindolo[3,2-g]...) Show SMILES CN1CCCc2ccccc2Cc2[nH]c3ccccc3c2CC1 Show InChI InChI=1S/C21H24N2/c1-23-13-6-9-16-7-2-3-8-17(16)15-21-19(12-14-23)18-10-4-5-11-20(18)22-21/h2-5,7-8,10-11,22H,6,9,12-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universit£t Jena Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human cloned dopamine D2L receptor				Bioorg Med Chem Lett 18: 3809-13 (2008) Article DOI: 10.1016/j.bmcl.2008.04.081 BindingDB Entry DOI: 10.7270/Q23F4QWW
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50196234 (8-methyl-5,6,7,8,9,10,15,16-octahydroindolo[3,2-g]...) Show SMILES CN1CCCc2ccccc2Cc2[nH]c3ccccc3c2CC1 Show InChI InChI=1S/C21H24N2/c1-23-13-6-9-16-7-2-3-8-17(16)15-21-19(12-14-23)18-10-4-5-11-20(18)22-21/h2-5,7-8,10-11,22H,6,9,12-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D2L dopamine receptor expressed in CHO cells				J Med Chem 49: 6408-11 (2006) Article DOI: 10.1021/jm060213k BindingDB Entry DOI: 10.7270/Q2GT5MTB
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50196234 (8-methyl-5,6,7,8,9,10,15,16-octahydroindolo[3,2-g]...) Show SMILES CN1CCCc2ccccc2Cc2[nH]c3ccccc3c2CC1 Show InChI InChI=1S/C21H24N2/c1-23-13-6-9-16-7-2-3-8-17(16)15-21-19(12-14-23)18-10-4-5-11-20(18)22-21/h2-5,7-8,10-11,22H,6,9,12-15H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	98.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D4 dopamine receptor expressed in CHO cells				J Med Chem 49: 6408-11 (2006) Article DOI: 10.1021/jm060213k BindingDB Entry DOI: 10.7270/Q2GT5MTB
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50196234 (8-methyl-5,6,7,8,9,10,15,16-octahydroindolo[3,2-g]...) Show SMILES CN1CCCc2ccccc2Cc2[nH]c3ccccc3c2CC1 Show InChI InChI=1S/C21H24N2/c1-23-13-6-9-16-7-2-3-8-17(16)15-21-19(12-14-23)18-10-4-5-11-20(18)22-21/h2-5,7-8,10-11,22H,6,9,12-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	278	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universität Jena Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D3 receptor expressed in CHO cells				J Med Chem 49: 6408-11 (2006) Article DOI: 10.1021/jm060213k BindingDB Entry DOI: 10.7270/Q2GT5MTB
					More data for this Ligand-Target Pair