BDBM50196510 CHEMBL3946048
SMILES: N\C(=N/O)c1ccc(NC(=O)NCCc2ccccc2)cc1
InChI Key: InChIKey=JXKAQTGZACRJMM-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Histone deacetylase (HDAC1 and HDAC2) (Homo sapiens (Human)) | BDBM50196510 (CHEMBL3946048) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 304 | n/a | n/a | n/a | n/a | n/a | n/a |
Qilu Normal University Curated by ChEMBL | Assay Description Inhibition of HDAC1/HDAC2 in human HeLa cell nuclear extract preincubated for 20 mins followed by addition of HDAC green as substrate measured after ... | Bioorg Med Chem Lett 26: 4679-4683 (2016) Article DOI: 10.1016/j.bmcl.2016.08.073 BindingDB Entry DOI: 10.7270/Q2V69MKX | |||||||||||
More data for this Ligand-Target Pair |