BDBM50196698 CHEMBL390389::N-(1-(3-chlorobenzyl)pyrrolidin-3-yl)-1H-indazol-5-amine::N-[1-(3-chlorobenzyl)-3-pyrrolidyl]-N-(1H-5-indazolyl)amine

SMILES: Clc1cccc(CN2CCC(C2)Nc2ccc3[nH]ncc3c2)c1

InChI Key: InChIKey=DBLHWYWZXQGUJM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196698   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2/Rho-kinase (ROCK I) (Homo sapiens (Human))	BDBM50196698 (CHEMBL390389 | N-(1-(3-chlorobenzyl)pyrrolidin-3-y...) Show SMILES Clc1cccc(CN2CCC(C2)Nc2ccc3[nH]ncc3c2)c1 Show InChI InChI=1S/C18H19ClN4/c19-15-3-1-2-13(8-15)11-23-7-6-17(12-23)21-16-4-5-18-14(9-16)10-20-22-18/h1-5,8-10,17,21H,6-7,11-12H2,(H,20,22)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co. Ltd Curated by ChEMBL					Assay Description Inhibition of Rho kinase				Bioorg Med Chem 15: 350-64 (2006) Article DOI: 10.1016/j.bmc.2006.09.052 BindingDB Entry DOI: 10.7270/Q2T43TW5
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50196698 (CHEMBL390389 | N-(1-(3-chlorobenzyl)pyrrolidin-3-y...) Show SMILES Clc1cccc(CN2CCC(C2)Nc2ccc3[nH]ncc3c2)c1 Show InChI InChI=1S/C18H19ClN4/c19-15-3-1-2-13(8-15)11-23-7-6-17(12-23)21-16-4-5-18-14(9-16)10-20-22-18/h1-5,8-10,17,21H,6-7,11-12H2,(H,20,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co. Ltd Curated by ChEMBL					Assay Description Inhibition of MCP1-induced cell migration in U937 cells expressing CCR2 by chemotaxis assay				Bioorg Med Chem 15: 350-64 (2006) Article DOI: 10.1016/j.bmc.2006.09.052 BindingDB Entry DOI: 10.7270/Q2T43TW5
					More data for this Ligand-Target Pair