BDBM50196704 1-benzyl-N-(1H-5-indazolyl)piperidine-3-carboxamide::1-benzyl-N-(1H-indazol-5-yl)piperidine-3-carboxamide::CHEMBL415061

SMILES: O=C(Nc1ccc2[nH]ncc2c1)C1CCCN(Cc2ccccc2)C1

InChI Key: InChIKey=PUDPIQFNZNNYGT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196704   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2/Rho-kinase (ROCK I) (Homo sapiens (Human))	BDBM50196704 (1-benzyl-N-(1H-5-indazolyl)piperidine-3-carboxamid...) Show SMILES O=C(Nc1ccc2[nH]ncc2c1)C1CCCN(Cc2ccccc2)C1 Show InChI InChI=1S/C20H22N4O/c25-20(22-18-8-9-19-17(11-18)12-21-23-19)16-7-4-10-24(14-16)13-15-5-2-1-3-6-15/h1-3,5-6,8-9,11-12,16H,4,7,10,13-14H2,(H,21,23)(H,22,25)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co. Ltd Curated by ChEMBL					Assay Description Inhibition of Rho kinase				Bioorg Med Chem 15: 350-64 (2006) Article DOI: 10.1016/j.bmc.2006.09.052 BindingDB Entry DOI: 10.7270/Q2T43TW5
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50196704 (1-benzyl-N-(1H-5-indazolyl)piperidine-3-carboxamid...) Show SMILES O=C(Nc1ccc2[nH]ncc2c1)C1CCCN(Cc2ccccc2)C1 Show InChI InChI=1S/C20H22N4O/c25-20(22-18-8-9-19-17(11-18)12-21-23-19)16-7-4-10-24(14-16)13-15-5-2-1-3-6-15/h1-3,5-6,8-9,11-12,16H,4,7,10,13-14H2,(H,21,23)(H,22,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co. Ltd Curated by ChEMBL					Assay Description Inhibition of MCP1-induced cell migration in U937 cells expressing CCR2 by chemotaxis assay				Bioorg Med Chem 15: 350-64 (2006) Article DOI: 10.1016/j.bmc.2006.09.052 BindingDB Entry DOI: 10.7270/Q2T43TW5
					More data for this Ligand-Target Pair