BDBM50196706 CHEMBL225167::N-(1-(furan-2-ylmethyl)piperidin-3-yl)-1H-indazol-5-amine::N-[1-(2-furylmethyl)-3-piperidyl]-N-(1H-5-indazolyl)amine

SMILES: C(N1CCCC(C1)Nc1ccc2[nH]ncc2c1)c1ccco1

InChI Key: InChIKey=FLZNZODFDWZMJE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50196706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50196706 (CHEMBL225167 | N-(1-(furan-2-ylmethyl)piperidin-3-...) Show SMILES C(N1CCCC(C1)Nc1ccc2[nH]ncc2c1)c1ccco1 Show InChI InChI=1S/C17H20N4O/c1-3-15(11-21(7-1)12-16-4-2-8-22-16)19-14-5-6-17-13(9-14)10-18-20-17/h2,4-6,8-10,15,19H,1,3,7,11-12H2,(H,18,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co. Ltd Curated by ChEMBL					Assay Description Inhibition of MCP1-induced cell migration in U937 cells expressing CCR2 by chemotaxis assay				Bioorg Med Chem 15: 350-64 (2006) Article DOI: 10.1016/j.bmc.2006.09.052 BindingDB Entry DOI: 10.7270/Q2T43TW5
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2/Rho-kinase (ROCK I) (Homo sapiens (Human))	BDBM50196706 (CHEMBL225167 | N-(1-(furan-2-ylmethyl)piperidin-3-...) Show SMILES C(N1CCCC(C1)Nc1ccc2[nH]ncc2c1)c1ccco1 Show InChI InChI=1S/C17H20N4O/c1-3-15(11-21(7-1)12-16-4-2-8-22-16)19-14-5-6-17-13(9-14)10-18-20-17/h2,4-6,8-10,15,19H,1,3,7,11-12H2,(H,18,20)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co. Ltd Curated by ChEMBL					Assay Description Inhibition of Rho kinase				Bioorg Med Chem 15: 350-64 (2006) Article DOI: 10.1016/j.bmc.2006.09.052 BindingDB Entry DOI: 10.7270/Q2T43TW5
					More data for this Ligand-Target Pair