BDBM50196725 CHEMBL224885::N-(1-benzyl-3-piperidyl)-N-(1H-5-indazolyl)amine::N-(1-benzylpiperidin-3-yl)-1H-indazol-5-amine

SMILES: C(N1CCCC(C1)Nc1ccc2[nH]ncc2c1)c1ccccc1

InChI Key: InChIKey=DNUAUADEIBLJGT-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50196725   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2/Rho-kinase (ROCK I) (Homo sapiens (Human))	BDBM50196725 (CHEMBL224885 | N-(1-benzyl-3-piperidyl)-N-(1H-5-in...) Show SMILES C(N1CCCC(C1)Nc1ccc2[nH]ncc2c1)c1ccccc1 Show InChI InChI=1S/C19H22N4/c1-2-5-15(6-3-1)13-23-10-4-7-18(14-23)21-17-8-9-19-16(11-17)12-20-22-19/h1-3,5-6,8-9,11-12,18,21H,4,7,10,13-14H2,(H,20,22)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co. Ltd Curated by ChEMBL					Assay Description Inhibition of Rho kinase				Bioorg Med Chem 15: 350-64 (2006) Article DOI: 10.1016/j.bmc.2006.09.052 BindingDB Entry DOI: 10.7270/Q2T43TW5
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50196725 (CHEMBL224885 | N-(1-benzyl-3-piperidyl)-N-(1H-5-in...) Show SMILES C(N1CCCC(C1)Nc1ccc2[nH]ncc2c1)c1ccccc1 Show InChI InChI=1S/C19H22N4/c1-2-5-15(6-3-1)13-23-10-4-7-18(14-23)21-17-8-9-19-16(11-17)12-20-22-19/h1-3,5-6,8-9,11-12,18,21H,4,7,10,13-14H2,(H,20,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co. Ltd Curated by ChEMBL					Assay Description Inhibition of MCP1-induced cell migration in U937 cells expressing CCR2 by chemotaxis assay				Bioorg Med Chem 15: 350-64 (2006) Article DOI: 10.1016/j.bmc.2006.09.052 BindingDB Entry DOI: 10.7270/Q2T43TW5
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2/Rho-kinase (ROCK I) (Homo sapiens (Human))	BDBM50196725 (CHEMBL224885 | N-(1-benzyl-3-piperidyl)-N-(1H-5-in...) Show SMILES C(N1CCCC(C1)Nc1ccc2[nH]ncc2c1)c1ccccc1 Show InChI InChI=1S/C19H22N4/c1-2-5-15(6-3-1)13-23-10-4-7-18(14-23)21-17-8-9-19-16(11-17)12-20-22-19/h1-3,5-6,8-9,11-12,18,21H,4,7,10,13-14H2,(H,20,22)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co. Ltd Curated by ChEMBL					Assay Description Inhibition of Rho kinase				Bioorg Med Chem 15: 350-64 (2006) Article DOI: 10.1016/j.bmc.2006.09.052 BindingDB Entry DOI: 10.7270/Q2T43TW5
					More data for this Ligand-Target Pair