Found 4 hits for monomerid = 50197019 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50197019
((2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)c1cccc(N)c1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |wU:74.76,75.79,4.4,92.94,20.28,59.61,112.114,wD:67.69,8.17,30.39,81.83,51.53,101.103,(11.09,-34.41,;11.09,-35.95,;12.43,-36.72,;9.76,-36.72,;9.76,-38.26,;8.42,-39.01,;7.09,-38.24,;7.09,-36.7,;5.76,-39.01,;5.76,-40.55,;7.09,-41.32,;8.42,-40.55,;9.76,-41.32,;9.76,-42.86,;11.07,-43.63,;8.42,-43.63,;7.09,-42.86,;4.42,-38.25,;3.1,-39.03,;3.1,-40.57,;1.77,-38.26,;1.77,-36.72,;3.1,-35.95,;4.5,-36.58,;5.54,-35.43,;4.77,-34.1,;3.26,-34.42,;.43,-39.02,;-.91,-38.25,;-.91,-36.71,;-2.23,-39.02,;-2.23,-40.56,;-.91,-41.33,;-.91,-42.87,;.43,-43.64,;.44,-45.18,;-.91,-45.94,;1.75,-45.94,;-3.57,-38.26,;-4.89,-39.04,;-4.89,-40.58,;-6.23,-38.27,;-6.23,-36.73,;-7.56,-35.97,;-8.89,-36.74,;-8.89,-38.28,;-10.22,-39.06,;-7.55,-39.05,;11.09,-39.03,;11.09,-40.57,;12.42,-38.25,;13.75,-39.02,;13.75,-40.56,;15.08,-41.33,;16.41,-40.55,;15.08,-42.87,;15.08,-38.25,;15.08,-36.71,;16.42,-39.01,;17.75,-38.25,;17.75,-36.71,;19.08,-35.94,;19.08,-34.4,;20.42,-36.71,;19.08,-39.02,;19.08,-40.56,;20.41,-38.24,;21.74,-39.02,;21.74,-40.56,;23.07,-41.33,;20.41,-41.33,;23.07,-38.25,;23.07,-36.71,;24.41,-39.02,;25.74,-38.25,;25.74,-36.71,;24.41,-35.94,;27.07,-35.93,;27.07,-39.02,;27.07,-40.56,;28.4,-38.24,;29.73,-39.01,;29.73,-40.55,;31.06,-41.32,;31.06,-42.86,;32.4,-43.63,;32.4,-45.17,;31.06,-45.93,;33.74,-45.93,;31.06,-38.24,;31.06,-36.7,;32.4,-39.01,;33.74,-38.25,;33.74,-36.71,;35.07,-35.94,;35.07,-34.4,;33.73,-33.62,;36.4,-33.63,;35.07,-39.02,;35.07,-40.56,;36.4,-38.24,;37.73,-39.02,;37.73,-40.56,;39.06,-41.33,;39.06,-42.87,;40.39,-43.63,;40.39,-45.17,;39.06,-45.93,;41.73,-45.93,;39.06,-38.25,;39.06,-36.71,;40.39,-39.01,;41.73,-38.25,;41.73,-36.71,;43.06,-35.94,;44.39,-36.71,;45.73,-35.94,;45.73,-34.4,;47.06,-33.63,;44.39,-33.63,;43.06,-34.4,;43.06,-39.02,;44.39,-38.25,;43.06,-40.56,)| Show InChI InChI=1S/C79H121N27O18/c1-39(2)30-55(100-71(119)57(33-44-19-23-49(109)24-20-44)102-72(120)58(35-47-37-90-38-94-47)103-68(116)50(14-9-27-91-77(84)85)95-65(113)45-12-8-13-46(80)34-45)70(118)104-59(36-61(82)111)73(121)101-56(31-40(3)4)74(122)105-62(41(5)6)75(123)106-63(42(7)107)76(124)98-52(16-11-29-93-79(88)89)66(114)97-53(25-26-60(81)110)69(117)96-51(15-10-28-92-78(86)87)67(115)99-54(64(83)112)32-43-17-21-48(108)22-18-43/h8,12-13,17-24,34,37-42,50-59,62-63,107-109H,9-11,14-16,25-33,35-36,80H2,1-7H3,(H2,81,110)(H2,82,111)(H2,83,112)(H,90,94)(H,95,113)(H,96,117)(H,97,114)(H,98,124)(H,99,115)(H,100,119)(H,101,121)(H,102,120)(H,103,116)(H,104,118)(H,105,122)(H,106,123)(H4,84,85,91)(H4,86,87,92)(H4,88,89,93)/t42-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,62+,63+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation
Curated by ChEMBL
| Assay Description
Displacement of human [125I]PYY from NPY2 receptor expressed in human KAN-TS cells |
Bioorg Med Chem Lett 17: 538-41 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.007
BindingDB Entry DOI: 10.7270/Q2959H6F |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50197019
((2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)c1cccc(N)c1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |wU:74.76,75.79,4.4,92.94,20.28,59.61,112.114,wD:67.69,8.17,30.39,81.83,51.53,101.103,(11.09,-34.41,;11.09,-35.95,;12.43,-36.72,;9.76,-36.72,;9.76,-38.26,;8.42,-39.01,;7.09,-38.24,;7.09,-36.7,;5.76,-39.01,;5.76,-40.55,;7.09,-41.32,;8.42,-40.55,;9.76,-41.32,;9.76,-42.86,;11.07,-43.63,;8.42,-43.63,;7.09,-42.86,;4.42,-38.25,;3.1,-39.03,;3.1,-40.57,;1.77,-38.26,;1.77,-36.72,;3.1,-35.95,;4.5,-36.58,;5.54,-35.43,;4.77,-34.1,;3.26,-34.42,;.43,-39.02,;-.91,-38.25,;-.91,-36.71,;-2.23,-39.02,;-2.23,-40.56,;-.91,-41.33,;-.91,-42.87,;.43,-43.64,;.44,-45.18,;-.91,-45.94,;1.75,-45.94,;-3.57,-38.26,;-4.89,-39.04,;-4.89,-40.58,;-6.23,-38.27,;-6.23,-36.73,;-7.56,-35.97,;-8.89,-36.74,;-8.89,-38.28,;-10.22,-39.06,;-7.55,-39.05,;11.09,-39.03,;11.09,-40.57,;12.42,-38.25,;13.75,-39.02,;13.75,-40.56,;15.08,-41.33,;16.41,-40.55,;15.08,-42.87,;15.08,-38.25,;15.08,-36.71,;16.42,-39.01,;17.75,-38.25,;17.75,-36.71,;19.08,-35.94,;19.08,-34.4,;20.42,-36.71,;19.08,-39.02,;19.08,-40.56,;20.41,-38.24,;21.74,-39.02,;21.74,-40.56,;23.07,-41.33,;20.41,-41.33,;23.07,-38.25,;23.07,-36.71,;24.41,-39.02,;25.74,-38.25,;25.74,-36.71,;24.41,-35.94,;27.07,-35.93,;27.07,-39.02,;27.07,-40.56,;28.4,-38.24,;29.73,-39.01,;29.73,-40.55,;31.06,-41.32,;31.06,-42.86,;32.4,-43.63,;32.4,-45.17,;31.06,-45.93,;33.74,-45.93,;31.06,-38.24,;31.06,-36.7,;32.4,-39.01,;33.74,-38.25,;33.74,-36.71,;35.07,-35.94,;35.07,-34.4,;33.73,-33.62,;36.4,-33.63,;35.07,-39.02,;35.07,-40.56,;36.4,-38.24,;37.73,-39.02,;37.73,-40.56,;39.06,-41.33,;39.06,-42.87,;40.39,-43.63,;40.39,-45.17,;39.06,-45.93,;41.73,-45.93,;39.06,-38.25,;39.06,-36.71,;40.39,-39.01,;41.73,-38.25,;41.73,-36.71,;43.06,-35.94,;44.39,-36.71,;45.73,-35.94,;45.73,-34.4,;47.06,-33.63,;44.39,-33.63,;43.06,-34.4,;43.06,-39.02,;44.39,-38.25,;43.06,-40.56,)| Show InChI InChI=1S/C79H121N27O18/c1-39(2)30-55(100-71(119)57(33-44-19-23-49(109)24-20-44)102-72(120)58(35-47-37-90-38-94-47)103-68(116)50(14-9-27-91-77(84)85)95-65(113)45-12-8-13-46(80)34-45)70(118)104-59(36-61(82)111)73(121)101-56(31-40(3)4)74(122)105-62(41(5)6)75(123)106-63(42(7)107)76(124)98-52(16-11-29-93-79(88)89)66(114)97-53(25-26-60(81)110)69(117)96-51(15-10-28-92-78(86)87)67(115)99-54(64(83)112)32-43-17-21-48(108)22-18-43/h8,12-13,17-24,34,37-42,50-59,62-63,107-109H,9-11,14-16,25-33,35-36,80H2,1-7H3,(H2,81,110)(H2,82,111)(H2,83,112)(H,90,94)(H,95,113)(H,96,117)(H,97,114)(H,98,124)(H,99,115)(H,100,119)(H,101,121)(H,102,120)(H,103,116)(H,104,118)(H,105,122)(H,106,123)(H4,84,85,91)(H4,86,87,92)(H4,88,89,93)/t42-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,62+,63+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from NPY1 receptor expressed in human SK-N-MC cells |
Bioorg Med Chem Lett 17: 538-41 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.007
BindingDB Entry DOI: 10.7270/Q2959H6F |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50197019
((2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)c1cccc(N)c1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |wU:74.76,75.79,4.4,92.94,20.28,59.61,112.114,wD:67.69,8.17,30.39,81.83,51.53,101.103,(11.09,-34.41,;11.09,-35.95,;12.43,-36.72,;9.76,-36.72,;9.76,-38.26,;8.42,-39.01,;7.09,-38.24,;7.09,-36.7,;5.76,-39.01,;5.76,-40.55,;7.09,-41.32,;8.42,-40.55,;9.76,-41.32,;9.76,-42.86,;11.07,-43.63,;8.42,-43.63,;7.09,-42.86,;4.42,-38.25,;3.1,-39.03,;3.1,-40.57,;1.77,-38.26,;1.77,-36.72,;3.1,-35.95,;4.5,-36.58,;5.54,-35.43,;4.77,-34.1,;3.26,-34.42,;.43,-39.02,;-.91,-38.25,;-.91,-36.71,;-2.23,-39.02,;-2.23,-40.56,;-.91,-41.33,;-.91,-42.87,;.43,-43.64,;.44,-45.18,;-.91,-45.94,;1.75,-45.94,;-3.57,-38.26,;-4.89,-39.04,;-4.89,-40.58,;-6.23,-38.27,;-6.23,-36.73,;-7.56,-35.97,;-8.89,-36.74,;-8.89,-38.28,;-10.22,-39.06,;-7.55,-39.05,;11.09,-39.03,;11.09,-40.57,;12.42,-38.25,;13.75,-39.02,;13.75,-40.56,;15.08,-41.33,;16.41,-40.55,;15.08,-42.87,;15.08,-38.25,;15.08,-36.71,;16.42,-39.01,;17.75,-38.25,;17.75,-36.71,;19.08,-35.94,;19.08,-34.4,;20.42,-36.71,;19.08,-39.02,;19.08,-40.56,;20.41,-38.24,;21.74,-39.02,;21.74,-40.56,;23.07,-41.33,;20.41,-41.33,;23.07,-38.25,;23.07,-36.71,;24.41,-39.02,;25.74,-38.25,;25.74,-36.71,;24.41,-35.94,;27.07,-35.93,;27.07,-39.02,;27.07,-40.56,;28.4,-38.24,;29.73,-39.01,;29.73,-40.55,;31.06,-41.32,;31.06,-42.86,;32.4,-43.63,;32.4,-45.17,;31.06,-45.93,;33.74,-45.93,;31.06,-38.24,;31.06,-36.7,;32.4,-39.01,;33.74,-38.25,;33.74,-36.71,;35.07,-35.94,;35.07,-34.4,;33.73,-33.62,;36.4,-33.63,;35.07,-39.02,;35.07,-40.56,;36.4,-38.24,;37.73,-39.02,;37.73,-40.56,;39.06,-41.33,;39.06,-42.87,;40.39,-43.63,;40.39,-45.17,;39.06,-45.93,;41.73,-45.93,;39.06,-38.25,;39.06,-36.71,;40.39,-39.01,;41.73,-38.25,;41.73,-36.71,;43.06,-35.94,;44.39,-36.71,;45.73,-35.94,;45.73,-34.4,;47.06,-33.63,;44.39,-33.63,;43.06,-34.4,;43.06,-39.02,;44.39,-38.25,;43.06,-40.56,)| Show InChI InChI=1S/C79H121N27O18/c1-39(2)30-55(100-71(119)57(33-44-19-23-49(109)24-20-44)102-72(120)58(35-47-37-90-38-94-47)103-68(116)50(14-9-27-91-77(84)85)95-65(113)45-12-8-13-46(80)34-45)70(118)104-59(36-61(82)111)73(121)101-56(31-40(3)4)74(122)105-62(41(5)6)75(123)106-63(42(7)107)76(124)98-52(16-11-29-93-79(88)89)66(114)97-53(25-26-60(81)110)69(117)96-51(15-10-28-92-78(86)87)67(115)99-54(64(83)112)32-43-17-21-48(108)22-18-43/h8,12-13,17-24,34,37-42,50-59,62-63,107-109H,9-11,14-16,25-33,35-36,80H2,1-7H3,(H2,81,110)(H2,82,111)(H2,83,112)(H,90,94)(H,95,113)(H,96,117)(H,97,114)(H,98,124)(H,99,115)(H,100,119)(H,101,121)(H,102,120)(H,103,116)(H,104,118)(H,105,122)(H,106,123)(H4,84,85,91)(H4,86,87,92)(H4,88,89,93)/t42-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,62+,63+/m1/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation
Curated by ChEMBL
| Assay Description
Displacement of [125I]PYY from NPY5 receptor expressed in human HEK293 cells |
Bioorg Med Chem Lett 17: 538-41 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.007
BindingDB Entry DOI: 10.7270/Q2959H6F |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50197019
((2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-...)Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)c1cccc(N)c1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O |wU:74.76,75.79,4.4,92.94,20.28,59.61,112.114,wD:67.69,8.17,30.39,81.83,51.53,101.103,(11.09,-34.41,;11.09,-35.95,;12.43,-36.72,;9.76,-36.72,;9.76,-38.26,;8.42,-39.01,;7.09,-38.24,;7.09,-36.7,;5.76,-39.01,;5.76,-40.55,;7.09,-41.32,;8.42,-40.55,;9.76,-41.32,;9.76,-42.86,;11.07,-43.63,;8.42,-43.63,;7.09,-42.86,;4.42,-38.25,;3.1,-39.03,;3.1,-40.57,;1.77,-38.26,;1.77,-36.72,;3.1,-35.95,;4.5,-36.58,;5.54,-35.43,;4.77,-34.1,;3.26,-34.42,;.43,-39.02,;-.91,-38.25,;-.91,-36.71,;-2.23,-39.02,;-2.23,-40.56,;-.91,-41.33,;-.91,-42.87,;.43,-43.64,;.44,-45.18,;-.91,-45.94,;1.75,-45.94,;-3.57,-38.26,;-4.89,-39.04,;-4.89,-40.58,;-6.23,-38.27,;-6.23,-36.73,;-7.56,-35.97,;-8.89,-36.74,;-8.89,-38.28,;-10.22,-39.06,;-7.55,-39.05,;11.09,-39.03,;11.09,-40.57,;12.42,-38.25,;13.75,-39.02,;13.75,-40.56,;15.08,-41.33,;16.41,-40.55,;15.08,-42.87,;15.08,-38.25,;15.08,-36.71,;16.42,-39.01,;17.75,-38.25,;17.75,-36.71,;19.08,-35.94,;19.08,-34.4,;20.42,-36.71,;19.08,-39.02,;19.08,-40.56,;20.41,-38.24,;21.74,-39.02,;21.74,-40.56,;23.07,-41.33,;20.41,-41.33,;23.07,-38.25,;23.07,-36.71,;24.41,-39.02,;25.74,-38.25,;25.74,-36.71,;24.41,-35.94,;27.07,-35.93,;27.07,-39.02,;27.07,-40.56,;28.4,-38.24,;29.73,-39.01,;29.73,-40.55,;31.06,-41.32,;31.06,-42.86,;32.4,-43.63,;32.4,-45.17,;31.06,-45.93,;33.74,-45.93,;31.06,-38.24,;31.06,-36.7,;32.4,-39.01,;33.74,-38.25,;33.74,-36.71,;35.07,-35.94,;35.07,-34.4,;33.73,-33.62,;36.4,-33.63,;35.07,-39.02,;35.07,-40.56,;36.4,-38.24,;37.73,-39.02,;37.73,-40.56,;39.06,-41.33,;39.06,-42.87,;40.39,-43.63,;40.39,-45.17,;39.06,-45.93,;41.73,-45.93,;39.06,-38.25,;39.06,-36.71,;40.39,-39.01,;41.73,-38.25,;41.73,-36.71,;43.06,-35.94,;44.39,-36.71,;45.73,-35.94,;45.73,-34.4,;47.06,-33.63,;44.39,-33.63,;43.06,-34.4,;43.06,-39.02,;44.39,-38.25,;43.06,-40.56,)| Show InChI InChI=1S/C79H121N27O18/c1-39(2)30-55(100-71(119)57(33-44-19-23-49(109)24-20-44)102-72(120)58(35-47-37-90-38-94-47)103-68(116)50(14-9-27-91-77(84)85)95-65(113)45-12-8-13-46(80)34-45)70(118)104-59(36-61(82)111)73(121)101-56(31-40(3)4)74(122)105-62(41(5)6)75(123)106-63(42(7)107)76(124)98-52(16-11-29-93-79(88)89)66(114)97-53(25-26-60(81)110)69(117)96-51(15-10-28-92-78(86)87)67(115)99-54(64(83)112)32-43-17-21-48(108)22-18-43/h8,12-13,17-24,34,37-42,50-59,62-63,107-109H,9-11,14-16,25-33,35-36,80H2,1-7H3,(H2,81,110)(H2,82,111)(H2,83,112)(H,90,94)(H,95,113)(H,96,117)(H,97,114)(H,98,124)(H,99,115)(H,100,119)(H,101,121)(H,102,120)(H,103,116)(H,104,118)(H,105,122)(H,106,123)(H4,84,85,91)(H4,86,87,92)(H4,88,89,93)/t42-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,62+,63+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Bayer Pharmaceuticals Corporation
Curated by ChEMBL
| Assay Description
Agonist activity at human NPY2 receptor expressed in human KAN-TS cells by [35S]GTPgammaS incorporation assay |
Bioorg Med Chem Lett 17: 538-41 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.007
BindingDB Entry DOI: 10.7270/Q2959H6F |
More data for this
Ligand-Target Pair | |
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