BDBM50197125 CHEMBL386021::N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-5-chloro-4-oxo-4H-chromene-2-carboxamide

SMILES: Clc1cccc2oc(cc(=O)c12)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1

InChI Key: InChIKey=QBCUHKWADQSBQG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197125   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50197125 (CHEMBL386021 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...) Show SMILES Clc1cccc2oc(cc(=O)c12)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C23H21ClN2O5/c24-16-2-1-3-19-22(16)17(27)11-21(31-19)23(28)25-15-6-8-26(9-7-15)12-14-4-5-18-20(10-14)30-13-29-18/h1-5,10-11,15H,6-9,12-13H2,(H,25,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at MCHr1 assessed as inhibition of MCH-mediated calcium ion release in intact IMR32 cells by FLIPR assay				J Med Chem 49: 6569-84 (2006) Article DOI: 10.1021/jm060683e BindingDB Entry DOI: 10.7270/Q2NG4Q7P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50197125 (CHEMBL386021 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...) Show SMILES Clc1cccc2oc(cc(=O)c12)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C23H21ClN2O5/c24-16-2-1-3-19-22(16)17(27)11-21(31-19)23(28)25-15-6-8-26(9-7-15)12-14-4-5-18-20(10-14)30-13-29-18/h1-5,10-11,15H,6-9,12-13H2,(H,25,28)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCH from MCHr1 expressed in IMR32 cells				J Med Chem 49: 6569-84 (2006) Article DOI: 10.1021/jm060683e BindingDB Entry DOI: 10.7270/Q2NG4Q7P
					More data for this Ligand-Target Pair