BDBM50197131 CHEMBL214377::N-[1-(1,3-benzodioxol-5-ylmethyl)piperidin-4-yl]-7-ethyl-4-oxo-4H-chromene-2-carboxamide

SMILES: CCc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1

InChI Key: InChIKey=DOYKZJFYZSSDTP-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50197131   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50197131 (CHEMBL214377 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...) Show SMILES CCc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C25H26N2O5/c1-2-16-3-5-19-20(28)13-24(32-22(19)11-16)25(29)26-18-7-9-27(10-8-18)14-17-4-6-21-23(12-17)31-15-30-21/h3-6,11-13,18H,2,7-10,14-15H2,1H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCH from MCHr1 expressed in IMR32 cells				J Med Chem 49: 6569-84 (2006) Article DOI: 10.1021/jm060683e BindingDB Entry DOI: 10.7270/Q2NG4Q7P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50197131 (CHEMBL214377 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...) Show SMILES CCc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C25H26N2O5/c1-2-16-3-5-19-20(28)13-24(32-22(19)11-16)25(29)26-18-7-9-27(10-8-18)14-17-4-6-21-23(12-17)31-15-30-21/h3-6,11-13,18H,2,7-10,14-15H2,1H3,(H,26,29)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	529	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at MCHr1 assessed as inhibition of MCH-mediated calcium ion release in intact IMR32 cells by FLIPR assay				J Med Chem 49: 6569-84 (2006) Article DOI: 10.1021/jm060683e BindingDB Entry DOI: 10.7270/Q2NG4Q7P
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50197131 (CHEMBL214377 | N-[1-(1,3-benzodioxol-5-ylmethyl)pi...) Show SMILES CCc1ccc2c(c1)oc(cc2=O)C(=O)NC1CCN(Cc2ccc3OCOc3c2)CC1 Show InChI InChI=1S/C25H26N2O5/c1-2-16-3-5-19-20(28)13-24(32-22(19)11-16)25(29)26-18-7-9-27(10-8-18)14-17-4-6-21-23(12-17)31-15-30-21/h3-6,11-13,18H,2,7-10,14-15H2,1H3,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from hERG				J Med Chem 49: 6569-84 (2006) Article DOI: 10.1021/jm060683e BindingDB Entry DOI: 10.7270/Q2NG4Q7P
					More data for this Ligand-Target Pair