null

SMILES: CC(=O)Nc1ccc(CN2CCC(CC2)NC(=O)c2cc(=O)c3ccc(F)cc3o2)cc1

InChI Key: InChIKey=AXOYDNAEBFRXFX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50197141   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50197141 (CHEMBL216680 | N-(1-(4-acetamidobenzyl)piperidin-4...) Show SMILES CC(=O)Nc1ccc(CN2CCC(CC2)NC(=O)c2cc(=O)c3ccc(F)cc3o2)cc1 Show InChI InChI=1S/C24H24FN3O4/c1-15(29)26-18-5-2-16(3-6-18)14-28-10-8-19(9-11-28)27-24(31)23-13-21(30)20-7-4-17(25)12-22(20)32-23/h2-7,12-13,19H,8-11,14H2,1H3,(H,26,29)(H,27,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]MCH from MCHr1 expressed in IMR32 cells				J Med Chem 49: 6569-84 (2006) Article DOI: 10.1021/jm060683e BindingDB Entry DOI: 10.7270/Q2NG4Q7P
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50197141 (CHEMBL216680 | N-(1-(4-acetamidobenzyl)piperidin-4...) Show SMILES CC(=O)Nc1ccc(CN2CCC(CC2)NC(=O)c2cc(=O)c3ccc(F)cc3o2)cc1 Show InChI InChI=1S/C24H24FN3O4/c1-15(29)26-18-5-2-16(3-6-18)14-28-10-8-19(9-11-28)27-24(31)23-13-21(30)20-7-4-17(25)12-22(20)32-23/h2-7,12-13,19H,8-11,14H2,1H3,(H,26,29)(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47.7	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from hERG				J Med Chem 49: 6569-84 (2006) Article DOI: 10.1021/jm060683e BindingDB Entry DOI: 10.7270/Q2NG4Q7P
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50197141 (CHEMBL216680 | N-(1-(4-acetamidobenzyl)piperidin-4...) Show SMILES CC(=O)Nc1ccc(CN2CCC(CC2)NC(=O)c2cc(=O)c3ccc(F)cc3o2)cc1 Show InChI InChI=1S/C24H24FN3O4/c1-15(29)26-18-5-2-16(3-6-18)14-28-10-8-19(9-11-28)27-24(31)23-13-21(30)20-7-4-17(25)12-22(20)32-23/h2-7,12-13,19H,8-11,14H2,1H3,(H,26,29)(H,27,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cells				Bioorg Med Chem Lett 17: 874-8 (2007) Article DOI: 10.1016/j.bmcl.2006.11.065 BindingDB Entry DOI: 10.7270/Q2D50MMK
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50197141 (CHEMBL216680 | N-(1-(4-acetamidobenzyl)piperidin-4...) Show SMILES CC(=O)Nc1ccc(CN2CCC(CC2)NC(=O)c2cc(=O)c3ccc(F)cc3o2)cc1 Show InChI InChI=1S/C24H24FN3O4/c1-15(29)26-18-5-2-16(3-6-18)14-28-10-8-19(9-11-28)27-24(31)23-13-21(30)20-7-4-17(25)12-22(20)32-23/h2-7,12-13,19H,8-11,14H2,1H3,(H,26,29)(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.77E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenates				Bioorg Med Chem Lett 17: 874-8 (2007) Article DOI: 10.1016/j.bmcl.2006.11.065 BindingDB Entry DOI: 10.7270/Q2D50MMK
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50197141 (CHEMBL216680 | N-(1-(4-acetamidobenzyl)piperidin-4...) Show SMILES CC(=O)Nc1ccc(CN2CCC(CC2)NC(=O)c2cc(=O)c3ccc(F)cc3o2)cc1 Show InChI InChI=1S/C24H24FN3O4/c1-15(29)26-18-5-2-16(3-6-18)14-28-10-8-19(9-11-28)27-24(31)23-13-21(30)20-7-4-17(25)12-22(20)32-23/h2-7,12-13,19H,8-11,14H2,1H3,(H,26,29)(H,27,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Antagonist activity at MCHr1 assessed as inhibition of MCH-mediated calcium ion release in intact IMR32 cells by FLIPR assay				J Med Chem 49: 6569-84 (2006) Article DOI: 10.1021/jm060683e BindingDB Entry DOI: 10.7270/Q2NG4Q7P
					More data for this Ligand-Target Pair