BDBM50197824 CHEMBL3983947

SMILES: Oc1cc(ccc1F)C(=O)c1cccc(n1)N1CCCCC1

InChI Key: InChIKey=OVJBJSXILIWMII-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50197824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
17-beta-hydroxysteroid dehydrogenase 14 (Homo sapiens (Human))	BDBM50197824 (CHEMBL3983947) Show SMILES Oc1cc(ccc1F)C(=O)c1cccc(n1)N1CCCCC1 Show InChI InChI=1S/C17H17FN2O2/c18-13-8-7-12(11-15(13)21)17(22)14-5-4-6-16(19-14)20-9-2-1-3-10-20/h4-8,11,21H,1-3,9-10H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	407	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Philipps University Marburg Curated by ChEMBL					Assay Description Inhibition of N-terminal 6His-tagged human human HSD17B14 expressed in Escherichia coli BL21 (DE3) pLysS using E2 substrate and NAD+ incubated for 2 ...				J Med Chem 59: 10719-10737 (2016) Article DOI: 10.1021/acs.jmedchem.6b01436 BindingDB Entry DOI: 10.7270/Q2KH0Q9S
					More data for this Ligand-Target Pair