BDBM50197913 (3R)-N-[1-(3-aminobenzyl)-3-pyrrolidyl]-N-(5-isoquinolyl)amine::CHEMBL387625

SMILES: Nc1cccc(CN2CC[C@H](C2)Nc2cccc3cnccc23)c1

InChI Key: InChIKey=KDILGLNJDNVPLP-GOSISDBHSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197913   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2/Rho-kinase (ROCK I) (Homo sapiens (Human))	BDBM50197913 ((3R)-N-[1-(3-aminobenzyl)-3-pyrrolidyl]-N-(5-isoqu...) Show SMILES Nc1cccc(CN2CC[C@H](C2)Nc2cccc3cnccc23)c1 Show InChI InChI=1S/C20H22N4/c21-17-5-1-3-15(11-17)13-24-10-8-18(14-24)23-20-6-2-4-16-12-22-9-7-19(16)20/h1-7,9,11-12,18,23H,8,10,13-14,21H2/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of Rho kinase				Bioorg Med Chem 15: 1022-33 (2006) Article DOI: 10.1016/j.bmc.2006.10.028 BindingDB Entry DOI: 10.7270/Q2XS5V1M
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50197913 ((3R)-N-[1-(3-aminobenzyl)-3-pyrrolidyl]-N-(5-isoqu...) Show SMILES Nc1cccc(CN2CC[C@H](C2)Nc2cccc3cnccc23)c1 Show InChI InChI=1S/C20H22N4/c21-17-5-1-3-15(11-17)13-24-10-8-18(14-24)23-20-6-2-4-16-12-22-9-7-19(16)20/h1-7,9,11-12,18,23H,8,10,13-14,21H2/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kirin Brewery Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of MCP1-induced chemotaxis in U937 cells overexpressing CCR2				Bioorg Med Chem 15: 1022-33 (2006) Article DOI: 10.1016/j.bmc.2006.10.028 BindingDB Entry DOI: 10.7270/Q2XS5V1M
					More data for this Ligand-Target Pair