BDBM50198230 (S)-2-((S)-(2-iodophenoxy)(phenyl)methyl)morpholine::CHEMBL393236
SMILES: Ic1ccccc1O[C@H]([C@@H]1CNCCO1)c1ccccc1
InChI Key: InChIKey=BHMLFPOTZYRDKA-IRXDYDNUSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Norepinephrine Monoamine transporters (Rattus norvegicus) | BDBM50198230 ((S)-2-((S)-(2-iodophenoxy)(phenyl)methyl)morpholin...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.840 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Degenerative Diseases Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from NET in rat brain membranes | Bioorg Med Chem Lett 17: 533-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.018 BindingDB Entry DOI: 10.7270/Q2WS8SX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus (rat)) | BDBM50198230 ((S)-2-((S)-(2-iodophenoxy)(phenyl)methyl)morpholin...) | Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.840 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Glasgow Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysis | Bioorg Med Chem Lett 19: 4996-8 (2009) Article DOI: 10.1016/j.bmcl.2009.07.064 BindingDB Entry DOI: 10.7270/Q22V2G5N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50198230 ((S)-2-((S)-(2-iodophenoxy)(phenyl)methyl)morpholin...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 40.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Degenerative Diseases Curated by ChEMBL | Assay Description Displacement of [3H]paroxetine from SERT in brain membranes | Bioorg Med Chem Lett 17: 533-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.018 BindingDB Entry DOI: 10.7270/Q2WS8SX8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50198230 ((S)-2-((S)-(2-iodophenoxy)(phenyl)methyl)morpholin...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 228 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Degenerative Diseases Curated by ChEMBL | Assay Description Displacement of [3H]GBR from DAT in rat brain membranes | Bioorg Med Chem Lett 17: 533-7 (2007) Article DOI: 10.1016/j.bmcl.2006.10.018 BindingDB Entry DOI: 10.7270/Q2WS8SX8 | |||||||||||
More data for this Ligand-Target Pair |