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SMILES: COc1ccc(cc1)-c1cc(=O)c2cc3ccoc3cc2o1

InChI Key: InChIKey=WXBAKLJXQYICHT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50198349   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50198349 (7-(4-methoxy-phenyl)-furo[3,2-g]chromen-5-one | CH...) Show SMILES COc1ccc(cc1)-c1cc(=O)c2cc3ccoc3cc2o1 Show InChI InChI=1S/C18H12O4/c1-20-13-4-2-11(3-5-13)17-9-15(19)14-8-12-6-7-21-16(12)10-18(14)22-17/h2-10H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of PTP1B				Bioorg Med Chem 15: 727-34 (2006) Article DOI: 10.1016/j.bmc.2006.10.053 BindingDB Entry DOI: 10.7270/Q2CR5T1W
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50198349 (7-(4-methoxy-phenyl)-furo[3,2-g]chromen-5-one | CH...) Show SMILES COc1ccc(cc1)-c1cc(=O)c2cc3ccoc3cc2o1 Show InChI InChI=1S/C18H12O4/c1-20-13-4-2-11(3-5-13)17-9-15(19)14-8-12-6-7-21-16(12)10-18(14)22-17/h2-10H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of PTP1B in presence of 0.01% Triton X-100				Bioorg Med Chem 15: 727-34 (2006) Article DOI: 10.1016/j.bmc.2006.10.053 BindingDB Entry DOI: 10.7270/Q2CR5T1W
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50198349 (7-(4-methoxy-phenyl)-furo[3,2-g]chromen-5-one | CH...) Show SMILES COc1ccc(cc1)-c1cc(=O)c2cc3ccoc3cc2o1 Show InChI InChI=1S/C18H12O4/c1-20-13-4-2-11(3-5-13)17-9-15(19)14-8-12-6-7-21-16(12)10-18(14)22-17/h2-10H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of PTP1B				Bioorg Med Chem 15: 727-34 (2006) Article DOI: 10.1016/j.bmc.2006.10.053 BindingDB Entry DOI: 10.7270/Q2CR5T1W
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50198349 (7-(4-methoxy-phenyl)-furo[3,2-g]chromen-5-one | CH...) Show SMILES COc1ccc(cc1)-c1cc(=O)c2cc3ccoc3cc2o1 Show InChI InChI=1S/C18H12O4/c1-20-13-4-2-11(3-5-13)17-9-15(19)14-8-12-6-7-21-16(12)10-18(14)22-17/h2-10H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of PTP1B in presence of 0.01% Triton X-100				Bioorg Med Chem 15: 727-34 (2006) Article DOI: 10.1016/j.bmc.2006.10.053 BindingDB Entry DOI: 10.7270/Q2CR5T1W
					More data for this Ligand-Target Pair